| Literature DB >> 2903956 |
S A Clark1, H B Angus, H B Cook, P M George, R B Oxner, R Fraser.
Abstract
The hepatic sinusoidal endothelium separates sinusoidal blood from hepatocytes; changes in the porosity of this endothelium may affect the passage of chylomicrons into hepatocytes and influence lipid metabolism. Chronic exposure to ethanol reduces the porosity of the endothelium; this mechanism may underlie the hyperlipoproteinaemia observed in some people who drink heavily.Entities:
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Year: 1988 PMID： 2903956 DOI： 10.1016/s0140-6736(88)90813-6
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321