Literature DB >> 29038883

[Multiple sclerosis in childhood and adolescence : Complex, chronic and differentiated].

A Blaschek1,2, P Huppke3, T Kümpfel4,5, W Müller-Felber6,7, K Rostasy8.   

Abstract

Pediatric multiple sclerosis (MS) is one of the most important acquired neurological disorders in childhood and adolescence. A timely recognition, diagnosis and treatment are of utmost importance. This article highlights the current state of knowledge on the etiology, pathogenesis, diagnosis, clinical presentation and treatment in childhood. Although the rate of progression of disability in the early years is slower in younger patients compared to adults, a disease-modifying therapy should be started once MS is diagnosed.

Entities:  

Keywords:  Encephalomyelitis; Magnetic resonance imaging; Methylprednisolone; Plasmapheresis; Symptom flare up; Therapy

Mesh:

Substances:

Year:  2017        PMID: 29038883     DOI: 10.1007/s00115-017-0422-z

Source DB:  PubMed          Journal:  Nervenarzt        ISSN: 0028-2804            Impact factor:   1.214


  25 in total

Review 1.  Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses.

Authors:  Lazaros Belbasis; Vanesa Bellou; Evangelos Evangelou; John P A Ioannidis; Ioanna Tzoulaki
Journal:  Lancet Neurol       Date:  2015-02-04       Impact factor: 44.182

2.  Effect of age at onset and parental disease status on sibling risks for MS.

Authors:  A D Sadovnick; I M Yee; G C Ebers; N J Risch
Journal:  Neurology       Date:  1998-03       Impact factor: 9.910

Review 3.  Differential diagnosis and evaluation in pediatric inflammatory demyelinating disorders.

Authors:  Kevin Rostasy; Barbara Bajer-Kornek; Sunita Venkateswaran; Cheryl Hemingway; Marc Tardieu
Journal:  Neurology       Date:  2016-08-30       Impact factor: 9.910

4.  Risk genes associated with pediatric-onset MS but not with monophasic acquired CNS demyelination.

Authors:  E Daniëlle van Pelt; Julia Y Mescheriakova; Nalia Makhani; Immy A Ketelslegers; Rinze F Neuteboom; Suman Kundu; Linda Broer; Cecile Janssens; Coriene E Catsman-Berrevoets; Cornelia M van Duijn; Brenda Banwell; Amit Bar-Or; Rogier Q Hintzen
Journal:  Neurology       Date:  2013-11-06       Impact factor: 9.910

5.  Multiple sclerosis in children and adolescents: incidence and clinical picture - new insights from the nationwide German surveillance (2009-2011).

Authors:  K Reinhardt; S Weiss; J Rosenbauer; J Gärtner; R von Kries
Journal:  Eur J Neurol       Date:  2014-01-28       Impact factor: 6.089

6.  Natural history of multiple sclerosis with childhood onset.

Authors:  Christel Renoux; Sandra Vukusic; Yann Mikaeloff; Gilles Edan; Michel Clanet; Bénédicte Dubois; Marc Debouverie; Bruno Brochet; Christine Lebrun-Frenay; Jean Pelletier; Thibault Moreau; Catherine Lubetzki; Patrick Vermersch; Etienne Roullet; Laurent Magy; Marc Tardieu; Samy Suissa; Christian Confavreux
Journal:  N Engl J Med       Date:  2007-06-21       Impact factor: 91.245

7.  Natalizumab use in pediatric multiple sclerosis.

Authors:  Peter Huppke; Wiebke Stark; Claudia Zürcher; Brenda Huppke; Wolfgang Brück; Jutta Gärtner
Journal:  Arch Neurol       Date:  2008-12

8.  Paediatric multiple sclerosis: the experience of the German Centre for Multiple Sclerosis in Childhood and Adolescence.

Authors:  Wiebke Stark; Peter Huppke; Jutta Gärtner
Journal:  J Neurol       Date:  2008-12       Impact factor: 4.849

9.  Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria.

Authors:  Chris H Polman; Stephen C Reingold; Brenda Banwell; Michel Clanet; Jeffrey A Cohen; Massimo Filippi; Kazuo Fujihara; Eva Havrdova; Michael Hutchinson; Ludwig Kappos; Fred D Lublin; Xavier Montalban; Paul O'Connor; Magnhild Sandberg-Wollheim; Alan J Thompson; Emmanuelle Waubant; Brian Weinshenker; Jerry S Wolinsky
Journal:  Ann Neurol       Date:  2011-02       Impact factor: 10.422

10.  Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D.

Authors:  Sreeram V Ramagopalan; Narelle J Maugeri; Lahiru Handunnetthi; Matthew R Lincoln; Sarah-Michelle Orton; David A Dyment; Gabriele C Deluca; Blanca M Herrera; Michael J Chao; A Dessa Sadovnick; George C Ebers; Julian C Knight
Journal:  PLoS Genet       Date:  2009-02-06       Impact factor: 5.917

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