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Literature DB >> 29038263

In Vitro Combination of Isavuconazole with Echinocandins against Azole-Susceptible and -Resistant Aspergillus spp.

A Raffetin^1,2, V Courbin^1,3, V Jullien^4,5, E Dannaoui^6,5.

Abstract

In vitro combinations of isavuconazole with echinocandins were evaluated against 30 Aspergillus strains with a two-dimensional checkerboard microdilution method and an agar-based diffusion method. With the checkerboard method, the three combinations showed indifferent interactions for all strains. With the agar-based method, indifferent interactions were found for all strains for isavuconazole-micafungin and isavuconazole-anidulafungin. For the isavuconazole-caspofungin combination, indifference was found in 24/30 strains, synergism in 4/30 strains, and antagonism in 2/30 strains.

Entities: Chemical

Keywords: Aspergillus spp.; EUCAST; MIC; combination; echinocandins; gradient strips; isavuconazole

Mesh：

Substances：

Year: 2017 PMID： 29038263 PMCID： PMC5740304 DOI： 10.1128/AAC.01382-17

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

39 in total

1. Combined activity in vitro of caspofungin, amphotericin B, and azole agents against itraconazole-resistant clinical isolates of Aspergillus fumigatus.

Authors: Manuel Cuenca-Estrella; Alicia Gomez-Lopez; Guillermo Garcia-Effron; Laura Alcazar-Fuoli; Emilia Mellado; Maria J Buitrago; Juan L Rodriguez-Tudela
Journal: Antimicrob Agents Chemother Date: 2005-03 Impact factor: 5.191

2. Spectrophotometric reading of EUCAST antifungal susceptibility testing of Aspergillus fumigatus.

Authors: J Meletiadis; K Leth Mortensen; P E Verweij; J W Mouton; M C Arendrup
Journal: Clin Microbiol Infect Date: 2016-10-25 Impact factor: 8.067

3. Monotherapy or combination therapy of isavuconazole and micafungin for treating murine mucormycosis.

Authors: Teclegiorgis Gebremariam; Nathan P Wiederhold; Abdullah Alqarihi; Priya Uppuluri; Nkechi Azie; John E Edwards; Ashraf S Ibrahim
Journal: J Antimicrob Chemother Date: 2016-10-24 Impact factor: 5.790

4. Prospective evaluation of azole resistance in Aspergillus fumigatus clinical isolates in France.

Authors: F Choukri; F Botterel; E Sitterlé; L Bassinet; F Foulet; J Guillot; J M Costa; N Fauchet; E Dannaoui
Journal: Med Mycol Date: 2015-05-30 Impact factor: 4.076

5. Azole resistance in Aspergillus fumigatus isolates from the ARTEMIS global surveillance study is primarily due to the TR/L98H mutation in the cyp51A gene.

Authors: Shawn R Lockhart; João P Frade; Kizee A Etienne; Michael A Pfaller; Daniel J Diekema; S Arunmozhi Balajee
Journal: Antimicrob Agents Chemother Date: 2011-06-20 Impact factor: 5.191

Review 6. Acquired antifungal drug resistance in Aspergillus fumigatus: epidemiology and detection.

Authors: Susan Julie Howard; Maiken Cavling Arendrup
Journal: Med Mycol Date: 2010-08-26 Impact factor: 4.076

7. In vitro susceptibilities of zygomycetes to conventional and new antifungals.

Authors: Eric Dannaoui; Joseph Meletiadis; Johan W Mouton; Jacques F G M Meis; Paul E Verweij
Journal: J Antimicrob Chemother Date: 2003-01 Impact factor: 5.790

8. Efficacy and pharmacodynamics of voriconazole combined with anidulafungin in azole-resistant invasive aspergillosis.

Authors: Seyedmojtaba Seyedmousavi; Roger J M Brüggemann; Willem J G Melchers; Antonius J M M Rijs; Paul E Verweij; Johan W Mouton
Journal: J Antimicrob Chemother Date: 2012-11-05 Impact factor: 5.790

9. In vitro interaction of voriconazole and anidulafungin against triazole-resistant Aspergillus fumigatus.

Authors: Seyedmojtaba Seyedmousavi; Joseph Meletiadis; Willem J G Melchers; Antonius J M M Rijs; Johan W Mouton; Paul E Verweij
Journal: Antimicrob Agents Chemother Date: 2012-11-26 Impact factor: 5.191

10. In vitro evaluation of double and triple combinations of antifungal drugs against Aspergillus fumigatus and Aspergillus terreus.

Authors: Eric Dannaoui; Olivier Lortholary; Françoise Dromer
Journal: Antimicrob Agents Chemother Date: 2004-03 Impact factor: 5.191

8 in total

Review 1. Echinocandins for the Treatment of Invasive Aspergillosis: from Laboratory to Bedside.

Authors: Marion Aruanno; Emmanouil Glampedakis; Frédéric Lamoth
Journal: Antimicrob Agents Chemother Date: 2019-07-25 Impact factor: 5.191

2. Antifungal Susceptibility Profiles and Drug Resistance Mechanisms of Clinical Lomentospora prolificans Isolates.

Authors: Yongqin Wu; Nina Grossman; Marissa Totten; Warda Memon; Anna Fitzgerald; Chunmei Ying; Sean X Zhang
Journal: Antimicrob Agents Chemother Date: 2020-10-20 Impact factor: 5.191

3. In vitro and in vivo interaction of caspofungin with isavuconazole against Candida auris planktonic cells and biofilms.

Authors: Fruzsina Nagy; Zoltán Tóth; Fanni Nyikos; Lajos Forgács; Ágnes Jakab; Andrew M Borman; László Majoros; Renátó Kovács
Journal: Med Mycol Date: 2021-10-04 Impact factor: 4.076

8. In vitro interaction of isavuconazole and anidulafungin against azole-susceptible and azole-resistant Aspergillus fumigatus isolates.

Authors: J B Buil; R J M Brüggemann; L Bedin Denardi; W J G Melchers; P E Verweij
Journal: J Antimicrob Chemother Date: 2020-09-01 Impact factor: 5.790