E Sahin1, D Dizdar2, M E Dinc3, A A Cirik4. 1. Department of Otolaryngology, Head and Neck Surgery,Bayındır Hospital Icerenkoy,Istanbul,Turkey. 2. Department of Otorhinolaryngology,Medical Park Bahçelievler Hospital,Faculty of Medicine,Istanbul Kemerburgaz University,Istanbul,Turkey. 3. Department of Otorhinolaryngology,Gaziosmanpasa Taksim Education and Research Hospital,Turkish Ministry of Health,Istanbul,Turkey. 4. Department of Otolaryngology,Head and Neck Surgery,Umraniye Research and Training Hospital,Istanbul,Turkey.
Abstract
BACKGROUND: Allergic rhinitis is strongly associated with the presence of house dust mites. This study investigated the long-term effects of allergen-specific immunotherapy. Allergen-specific immunotherapy was applied over three years. The study was based on a 10-year follow up of patients with allergic rhinitis. METHODS: The study was conducted between 2001 and 2015. Skin prick test results and symptom scores were evaluated before (26 patients) and after 3 years (20 patients) of allergen-specific immunotherapy (using data from a previously published study), and 10 years after allergen-specific immunotherapy had ended (20 of 26 patients). RESULTS: The symptom scores before allergen-specific immunotherapy were significantly higher than those obtained after 3 years of allergen-specific immunotherapy and 10 years after allergen-specific immunotherapy (p 0.0175). CONCLUSION: Subcutaneous immunotherapy is an effective treatment for house dust mite induced allergic rhinitis.
BACKGROUND:Allergic rhinitis is strongly associated with the presence of house dust mites. This study investigated the long-term effects of allergen-specific immunotherapy. Allergen-specific immunotherapy was applied over three years. The study was based on a 10-year follow up of patients with allergic rhinitis. METHODS: The study was conducted between 2001 and 2015. Skin prick test results and symptom scores were evaluated before (26 patients) and after 3 years (20 patients) of allergen-specific immunotherapy (using data from a previously published study), and 10 years after allergen-specific immunotherapy had ended (20 of 26 patients). RESULTS: The symptom scores before allergen-specific immunotherapy were significantly higher than those obtained after 3 years of allergen-specific immunotherapy and 10 years after allergen-specific immunotherapy (p 0.0175). CONCLUSION: Subcutaneous immunotherapy is an effective treatment for house dust mite induced allergic rhinitis.