Automatic classification of atherosclerotic tissue in intravascular optical coherence tomography images.

Intravascular optical coherence tomography (IVOCT) has been successfully utilized for in vivo diagnostics of coronary plaques. However, classification of atherosclerotic tissues is mainly performed manually by experienced experts, which is time-consuming and subjective. To overcome these limitations, an automatic method of segmentation and classification of IVOCT images is developed in this paper. The method is capable of detecting the plaque contour between the fibrous tissues and other components. Subsequently, the method classifies the tissues based on their texture features described by Fourier transform and discrete wavelet transform. The experimental results of 103 images show that an overall classification accuracy of over 80% in the indicator of depth and span angle is achieved in comparison to manual results. The validation suggests that this method is objective, accurate, and automatic without any manual intervention. The proposed method is able to demonstrate the artery wall morphology successfully, which is valuable for the research of atherosclerotic disease.