Literature DB >> 2903550

Cellular and molecular mechanisms of drug dependence.

G F Koob1, F E Bloom.   

Abstract

The molecular and cellular actions of three classes of abused drugs--opiates, psychostimulants, and ethanol--are reviewed in the context of behavioral studies of drug dependence. The immediate effects of drugs are compared to those observed after long-term exposure. A neurobiological basis for drug dependence is proposed from the linkage between the cellular and behavioral effects of these drugs.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 2903550     DOI： 10.1126/science.2903550

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  414 in total

1.  Blockade of D1 dopamine receptors in the ventral tegmental area decreases cocaine reward: possible role for dendritically released dopamine.

Authors:  R Ranaldi; R A Wise
Journal:  J Neurosci       Date:  2001-08-01       Impact factor: 6.167

Review 2.  Paradoxical signal transduction in neurobiological systems.

Authors:  F C Colpaert; Y Frégnac
Journal:  Mol Neurobiol       Date:  2001 Aug-Dec       Impact factor: 5.590

3.  Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission.

Authors:  Q Wu; M E Reith; M J Kuhar; F I Carroll; P A Garris
Journal:  J Neurosci       Date:  2001-08-15       Impact factor: 6.167

4.  Network synchrony in the nucleus accumbens in vivo.

Authors:  Y Goto; P O'Donnell
Journal:  J Neurosci       Date:  2001-06-15       Impact factor: 6.167

5.  Dopamine depresses excitatory and inhibitory synaptic transmission by distinct mechanisms in the nucleus accumbens.

Authors:  S M Nicola; R C Malenka
Journal:  J Neurosci       Date:  1997-08-01       Impact factor: 6.167

6.  Neurofunctional Domains Derived From Deep Behavioral Phenotyping in Alcohol Use Disorder.

Authors:  Laura E Kwako; Melanie L Schwandt; Vijay A Ramchandani; Nancy Diazgranados; George F Koob; Nora D Volkow; Carlos Blanco; David Goldman
Journal:  Am J Psychiatry       Date:  2019-01-04       Impact factor: 18.112

Review 7.  Animal models of drug craving.

Authors:  A Markou; F Weiss; L H Gold; S B Caine; G Schulteis; G F Koob
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

8.  Striatal regulation of morphine-induced hyperphagia: an anatomical mapping study.

Authors:  V P Bakshi; A E Kelley
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

9.  Immobilization stress-induced oral opioid self-administration and withdrawal in rats: role of conditioning factors and the effect of stress on "relapse" to opioid drugs.

Authors:  Y Shaham
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

10.  Dopamine efflux during withdrawal from continuous or intermittent cocaine.

Authors:  G R King; C Kuhn; E H Ellinwood
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.