Literature DB >> 29034480

Antioxidant therapy in a mouse model of Duchenne muscular dystrophy: some promising results but with a weighty caveat.

Stewart I Head1.   

Abstract

Entities:  

Keywords:  antioxidant; muscle contraction; muscular dystrophy

Mesh:

Substances:

Year:  2017        PMID: 29034480      PMCID: PMC5709324          DOI: 10.1113/JP275232

Source DB:  PubMed          Journal:  J Physiol        ISSN: 0022-3751            Impact factor:   5.182


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  5 in total

Review 1.  Why have antioxidants failed in clinical trials?

Authors:  Steven R Steinhubl
Journal:  Am J Cardiol       Date:  2008-05-22       Impact factor: 2.778

2.  N-Acetylcysteine treatment of dystrophic mdx mice results in protein thiol modifications and inhibition of exercise induced myofibre necrosis.

Authors:  Jessica R Terrill; Hannah G Radley-Crabb; Miranda D Grounds; Peter G Arthur
Journal:  Neuromuscul Disord       Date:  2011-12-27       Impact factor: 4.296

Review 3.  N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility.

Authors:  Seetal Dodd; Olivia Dean; David L Copolov; Gin S Malhi; Michael Berk
Journal:  Expert Opin Biol Ther       Date:  2008-12       Impact factor: 4.388

4.  Pre-clinical evaluation of N-acetylcysteine reveals side effects in the mdx mouse model of Duchenne muscular dystrophy.

Authors:  Gavin J Pinniger; Jessica R Terrill; Evanna B Assan; Miranda D Grounds; Peter G Arthur
Journal:  J Physiol       Date:  2017-09-30       Impact factor: 5.182

5.  N-Acetylcysteine ameliorates skeletal muscle pathophysiology in mdx mice.

Authors:  Nicholas P Whitehead; Catherine Pham; Othon L Gervasio; David G Allen
Journal:  J Physiol       Date:  2008-02-07       Impact factor: 5.182

  5 in total
  6 in total

1.  Antioxidant therapy for muscular dystrophy: caveat lector!

Authors:  Ken D O'Halloran; Kevin H Murphy; David P Burns
Journal:  J Physiol       Date:  2018-01-15       Impact factor: 5.182

Review 2.  Antioxidants to prevent respiratory decline in people with Duchenne muscular dystrophy and progressive respiratory decline.

Authors:  Luis Garegnani; Martin Hyland; Pablo Roson Rodriguez; Camila Micaela E Escobar Liquitay; Juan Va Franco
Journal:  Cochrane Database Syst Rev       Date:  2021-11-08

Review 3.  Antioxidants to prevent respiratory decline in people with Duchenne muscular dystrophy and progressive respiratory decline.

Authors:  Luis Garegnani; Martin Hyland; Pablo Roson Rodriguez; Camila Micaela Escobar Liquitay; Juan Va Franco
Journal:  Cochrane Database Syst Rev       Date:  2021-12-01

Review 4.  Progressive Skeletal Muscle Atrophy in Muscular Dystrophies: A Role for Toll-like Receptor-Signaling in Disease Pathogenesis.

Authors:  Boel De Paepe
Journal:  Int J Mol Sci       Date:  2020-06-22       Impact factor: 5.923

Review 5.  Teaching an Old Molecule New Tricks: Drug Repositioning for Duchenne Muscular Dystrophy.

Authors:  Libero Vitiello; Lucia Tibaudo; Elena Pegoraro; Luca Bello; Marcella Canton
Journal:  Int J Mol Sci       Date:  2019-11-30       Impact factor: 5.923

6.  N-acetylcysteine Decreases Fibrosis and Increases Force-Generating Capacity of mdx Diaphragm.

Authors:  David P Burns; Sarah E Drummond; Dearbhla Bolger; Amélie Coiscaud; Kevin H Murphy; Deirdre Edge; Ken D O'Halloran
Journal:  Antioxidants (Basel)       Date:  2019-11-24
  6 in total

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