Kurt Kroenke1, Erica Evans2, Sharon Weitlauf2, Stephanie McCalley2, Brian Porter2, Tabeel Williams2, Fitsum Baye3, Spencer G Lourens3, Marianne S Matthias4, Matthew J Bair5. 1. VA HSR&D Center for Health Information and Communication, Roudebush VA Medical Center, Indianapolis, IN, United States; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States; Regenstrief Institute, Inc., Indianapolis, IN, United States. Electronic address: kkroenke@regenstrief.org. 2. VA HSR&D Center for Health Information and Communication, Roudebush VA Medical Center, Indianapolis, IN, United States. 3. Department of Biostatistics, Fairbanks School of Public Health, Indianapolis, IN, United States. 4. VA HSR&D Center for Health Information and Communication, Roudebush VA Medical Center, Indianapolis, IN, United States; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States; Regenstrief Institute, Inc., Indianapolis, IN, United States; Department of Communication Studies, Indianapolis University-Purdue University at Indianapolis, Indianapolis, IN, United States. 5. VA HSR&D Center for Health Information and Communication, Roudebush VA Medical Center, Indianapolis, IN, United States; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States; Regenstrief Institute, Inc., Indianapolis, IN, United States.
Abstract
BACKGROUND: Pain is the most common presenting somatic symptom in medical outpatients, and depression and anxiety are the two most common mental disorders. They frequently co-occur, are under-treated, and result in substantial disability and reduced health-related quality of life. OBJECTIVES: The Comprehensive vs. Assisted Management of Mood and Pain Symptoms (CAMMPS) study is a randomized comparative effectiveness trial designed to test the relative effectiveness of a lower-resource vs. a higher-resource technology-assisted intervention for the management of patients suffering from pain plus anxiety and/or depression. METHODS/ DESIGN:CAMMPS has enrolled 294 primary care patients with chronic pain plus comorbid anxiety and/or depression and randomized them toeither: 1) Assisted Symptom Management (ASM) consisting of automated symptom monitoring by interactive voice recording or Internet and prompted pain and mood self-management; or 2) Comprehensive Symptom Management (CSM) which combines ASM with optimized medication management delivered by a nurse-physician specialist team and facilitated mental health care. Outcomes are assessed at baseline, 1, 3, 6, and 12months. The primary outcome is a composite pain-anxiety-depression (PAD) severity score. Secondary outcomes include individual pain, anxiety, and depression scores, health-related quality of life, disability, healthcare utilization, and treatment satisfaction. DISCUSSION: CAMMPS provides an integrated approach to PAD symptoms rather than fragmented care of single symptoms; coordinated symptom management in partnership with primary care clinicians and psychologists embedded in primary care; efficient use of health information technology; attention to physical and psychological symptom comorbidity; and the coupling of self-management with optimized medication management and facilitated mental health care. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT01757301. Published by Elsevier Inc.
RCT Entities:
BACKGROUND:Pain is the most common presenting somatic symptom in medical outpatients, and depression and anxiety are the two most common mental disorders. They frequently co-occur, are under-treated, and result in substantial disability and reduced health-related quality of life. OBJECTIVES: The Comprehensive vs. Assisted Management of Mood and Pain Symptoms (CAMMPS) study is a randomized comparative effectiveness trial designed to test the relative effectiveness of a lower-resource vs. a higher-resource technology-assisted intervention for the management of patients suffering from pain plus anxiety and/or depression. METHODS/ DESIGN: CAMMPS has enrolled 294 primary care patients with chronic pain plus comorbid anxiety and/or depression and randomized them to either: 1) Assisted Symptom Management (ASM) consisting of automated symptom monitoring by interactive voice recording or Internet and prompted pain and mood self-management; or 2) Comprehensive Symptom Management (CSM) which combines ASM with optimized medication management delivered by a nurse-physician specialist team and facilitated mental health care. Outcomes are assessed at baseline, 1, 3, 6, and 12months. The primary outcome is a composite pain-anxiety-depression (PAD) severity score. Secondary outcomes include individual pain, anxiety, and depression scores, health-related quality of life, disability, healthcare utilization, and treatment satisfaction. DISCUSSION: CAMMPS provides an integrated approach to PAD symptoms rather than fragmented care of single symptoms; coordinated symptom management in partnership with primary care clinicians and psychologists embedded in primary care; efficient use of health information technology; attention to physical and psychological symptom comorbidity; and the coupling of self-management with optimized medication management and facilitated mental health care. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT01757301. Published by Elsevier Inc.
Authors: Kurt Kroenke; Fitsum Baye; Spencer G Lourens; Erica Evans; Sharon Weitlauf; Stephanie McCalley; Brian Porter; Marianne S Matthias; Matthew J Bair Journal: J Gen Intern Med Date: 2019-06-21 Impact factor: 5.128
Authors: Kurt Kroenke; Tasneem L Talib; Timothy E Stump; Jacob Kean; David A Haggstrom; Paige DeChant; Kittie R Lake; Madison Stout; Patrick O Monahan Journal: J Gen Intern Med Date: 2018-04-05 Impact factor: 5.128
Authors: Kurt Kroenke; Timothy E Stump; Chen X Chen; Jacob Kean; Matthew J Bair; Teresa M Damush; Erin E Krebs; Patrick O Monahan Journal: J Affect Disord Date: 2020-01-23 Impact factor: 4.839
Authors: Chen X Chen; Kurt Kroenke; Timothy Stump; Jacob Kean; Erin E Krebs; Matthew J Bair; Teresa Damush; Patrick O Monahan Journal: J Pain Date: 2018-12-06 Impact factor: 5.820
Authors: Catherine E Mosher; Ekin Secinti; Wei Wu; Deborah A Kashy; Kurt Kroenke; Jonathan B Bricker; Paul R Helft; Anita A Turk; Patrick J Loehrer; Amikar Sehdev; Ahmad A Al-Hader; Victoria L Champion; Shelley A Johns Journal: Palliat Med Date: 2022-05-30 Impact factor: 5.713
Authors: Shirin ArdeshirRouhaniFard; Paul C Dinh; Patrick O Monahan; Sophie D Fossa; Robert Huddart; Chunkit Fung; Yiqing Song; Darren R Feldman; Robert J Hamilton; David J Vaughn; Neil E Martin; Christian Kollmannsberger; Lawrence Einhorn; Kurt Kroenke; Lois B Travis Journal: Cancer Epidemiol Biomarkers Prev Date: 2021-04-13 Impact factor: 4.254
Authors: Catherine E Mosher; Ekin Secinti; Kurt Kroenke; Paul R Helft; Anita A Turk; Patrick J Loehrer; Amikar Sehdev; Ahmad A Al-Hader; Victoria L Champion; Shelley A Johns Journal: Pilot Feasibility Stud Date: 2021-04-20