Literature DB >> 29031060

An insight into the biological activities of heterocyclic-fatty acid hybrid molecules.

Vijayendar Venepally1, Ram Chandra Reddy Jala2.   

Abstract

Heterocyclic compounds are the interesting core structures for the development of new bioactive compounds. Fatty acids are derived from renewable raw materials and exhibit various biological activities. Several researchers are amalgamating these two bioactive components to yield bioactive hybrid molecules with some desirable features. Heterocyclic-fatty acid hybrid derivatives are a new class of heterocyclic compounds with a broad range of biological activities and significance in the field of medicinal chemistry. Over the last few years, many research articles emphasized the significance of heterocyclic-fatty acid hybrid derivatives. The present review article focuses the developments in designing and biological evaluation of heterocyclic-fatty acid hybrid molecules.
Copyright © 2017. Published by Elsevier Masson SAS.

Entities:  

Keywords:  Biological activities; Fatty acids; Heterocyclic compounds; Hybrid molecules

Mesh:

Substances:

Year:  2017        PMID: 29031060     DOI: 10.1016/j.ejmech.2017.09.069

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  3 in total

1.  Synthesis and antitumoral activity of novel analogues monastrol-fatty acids against glioma cells.

Authors:  Franciele S De Oliveira; Patrick M De Oliveira; Luana M Farias; Rafael C Brinkerhoff; Rui Carlos M A Sobrinho; Tamara M Treptow; Caroline R Montes D'Oca; Marcelo A G Marinho; Mariana A Hort; Ana P Horn; Dennis Russowsky; Marcelo G Montes D'Oca
Journal:  Medchemcomm       Date:  2018-05-30       Impact factor: 3.597

2.  Exploration of NMI-MsCl mediated amide bond formation for the synthesis of novel 3,5-substituted-1,2,4-oxadiazole derivatives: synthesis, evaluation of anti-inflammatory activity and molecular docking studies.

Authors:  B Kulkarni; K Manjunatha; Muthipeedika Nibin Joy; Ayyiliath Meleveetil Sajith; Sougata Santra; Grigory V Zyryanov; C N Prashantha; Mohammed B Alshammari; K Sunil
Journal:  Mol Divers       Date:  2022-10-11       Impact factor: 3.364

3.  In Vitro and In Silico Study to Assess Toxic Mechanisms of Hybrid Molecules of Quinone-Benzocaine as Plastoquinone Analogues in Breast Cancer Cells.

Authors:  Ayse Mine Yilmaz Goler; Ayse Tarbin Jannuzzi; Nilüfer Bayrak; Mahmut Yıldız; Hatice Yıldırım; Masami Otsuka; Mikako Fujita; Mohamed O Radwan; Amaç Fatih TuYuN
Journal:  ACS Omega       Date:  2022-08-15
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.