Literature DB >> 2903069

In vitro enhancement of human platelet aggregation by somatostatin.

P P Gazzaniga1, G Di Macco, R La Mancusa, A Oddi, G Pappalardo, F M Pulcinelli, D Reggio.   

Abstract

Very low concentrations of somatostatin (S-14) strongly potentiate the in vitro aggregation induced by collagen, ristocetin and arachidonic acid, but not that induced by ADP or epinephrine, in both human platelet rich plasmas and gel-filtered platelet preparations. Desensitization phenomena may be induced either by repeated addition of S-14 or long lasting contact between S-14 and platelets.

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Year:  1988        PMID： 2903069     DOI： 10.1007/bf01941192

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  21 in total

1.  Effects of somatostatin on hemostasis in baboons.

Authors:  D J Koerker; L A Harker; C J Goodner
Journal:  N Engl J Med       Date:  1975-09-04       Impact factor: 91.245

2.  Nature and properties of human platelet vasopressin receptors.

Authors:  D Vittet; A Rondot; B Cantau; J M Launay; C Chevillard
Journal:  Biochem J       Date:  1986-02-01       Impact factor: 3.857

3.  The platelet reactivity of collagen type I: evidence for multiple platelet-reactive sites in the type I collagen molecule.

Authors:  C M Fitzsimmons; T E Cawston; M J Barnes
Journal:  Thromb Haemost       Date:  1986-08-20       Impact factor: 5.249

4.  Gel filtration of blood platelets: a methodological report.

Authors:  O Tangen; H J Berman
Journal:  Adv Exp Med Biol       Date:  1972       Impact factor: 2.622

5.  Somatostatin and ranitidine in the control of iatrogenic haemorrhage of the upper gastrointestinal tract.

Authors:  F Coraggio; P Scarpato; M Spina; S Lombardi
Journal:  Br Med J (Clin Res Ed)       Date:  1984-07-28

6.  Further studies on the significance of circulating platelet aggregates induced by somatostatin in man.

Authors:  D Giugliano; L Coppola; L Misso; A Tirelli; N Passariello; F D'Onofrio
Journal:  Metabolism       Date:  1981-02       Impact factor: 8.694

7.  Impairment of platelet function by growth-hormone release-inhibiting hormone.

Authors:  G M Besser; A M Paxton; S A Johnson; E J Moody; C H Mortimer
Journal:  Lancet       Date:  1975-05-24       Impact factor: 79.321

8.  Studies with a murine monoclonal antibody that abolishes ristocetin-induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor.

Authors:  B S Coller; E I Peerschke; L E Scudder; C A Sullivan
Journal:  Blood       Date:  1983-01       Impact factor: 22.113

9.  Somatostatin in the treatment of severe upper gastrointestinal bleeding: a multicentre controlled trial.

Authors:  A J Torres; I Landa; F Hernández; J M Jover; A Suárez; J Arias; R Cuberes; J Santoyo; R Fernández; J Calleja
Journal:  Br J Surg       Date:  1986-10       Impact factor: 6.939

10.  Ranitidine and somatostatin. Their effects on bleeding from the upper gastrointestinal tract.

Authors:  N Basso; M Bagarani; F Bracci; G Cucchiara; D Gizzonio; G Grassini; M Percoco; F Procacciante; F Toti
Journal:  Arch Surg       Date:  1986-07
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  1 in total

Review 1.  Somatostatin in acute bleeding oesophageal varices. Pharmacology and rationale for use.

Authors:  E Hanisch; J Doertenbach; K H Usadel
Journal:  Drugs       Date:  1992       Impact factor: 9.546
  1 in total

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