Ryoji Nagoshi1, Takayuki Okamura2, Yoshinobu Murasato3, Tatsuhiro Fujimura2, Masahiro Yamawaki4, Shiro Ono5, Takeshi Serikawa6, Yutaka Hikichi7, Fumiaki Nakao8, Tomohiro Sakamoto9, Toshiro Shinke10, Yoichi Kijima1, Amane Kozuki1, Hiroyuki Shibata1, Junya Shite11. 1. Department of Cardiology, Osaka Saiseikai Nakatsu Hospital, Japan. 2. Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, Japan. 3. Department of Cardiology, Kyusyu Medical Center, Japan. 4. Department of Cardiology, Saiseikai Yokohama Eastern Hospital, Japan. 5. Department of Cardiology, Saiseikai Yamaguchi General Hospital, Japan. 6. Department of Cardiology, Saiseikai Fukuoka General Hospital, Japan. 7. Department of Cardiology, Oda Hospital, Japan. 8. Department of Cardiology, Yamaguchi Central General Hospital, Japan. 9. Department of Cardiology, Saiseikai Kumamoto General Hospital, Japan. 10. Department of Cardiology, Kobe University Graduate School of Medicine, Japan. 11. Department of Cardiology, Osaka Saiseikai Nakatsu Hospital, Japan. Electronic address: shite@med.kobe-u.ac.jp.
Abstract
BACKGROUND: For the treatment of coronary bifurcation lesions, optimal guidewire (GW) recrossing after main vessel stenting is important for good stent apposition at the side branch (SB) orifice in kissing balloon inflation (KBI). METHODS: We analyzed 150 bifurcation lesions treated with single stenting following KBI in the three-dimensional optical coherence tomography (3D-OCT) bifurcation registry study (2015-16) and a single center experience (2012-16). OCT examination was performed after GW recrossing to the SB and after KBI. Patients were divided into two-dimensional (2D, n=78) and 3D groups (n=72) according to 2D- or 3D-OCT guidance. GW recrossing position, jailing configuration of the stent over the SB (divided into Link-connecting type: stent link connecting to the carina and Link-free type: no stent link at the carina) and stent apposition were compared between the groups. RESULTS: Distal GW recrossing was achieved in 75.6% and 91.7% in the 2D and 3D groups, respectively (P=0.004). Compared with the 2D group, the incidence of incomplete stent apposition (ISA) toward the SB in the 3D group tended to be lower in the whole cohort (14.5±13.6% vs 10.0±9.0%, P=0.077), and was significantly lower in left main trunk bifurcations (18.7±12.8% vs 10.3±8.9%, P=0.014). Independent contributors to ISA were the Link-connecting type (β 0.089, P<0.001), distal GW recrossing (β -0.078, P=0.001), and age (β -0.0020, P=0.012). CONCLUSION: Optimal GW recrossing under 3D-OCT guidance is feasible and improves stent apposition, which may lead to a better clinical outcome in the treatment of bifurcation lesions.
BACKGROUND: For the treatment of coronary bifurcation lesions, optimal guidewire (GW) recrossing after main vessel stenting is important for good stent apposition at the side branch (SB) orifice in kissing balloon inflation (KBI). METHODS: We analyzed 150 bifurcation lesions treated with single stenting following KBI in the three-dimensional optical coherence tomography (3D-OCT) bifurcation registry study (2015-16) and a single center experience (2012-16). OCT examination was performed after GW recrossing to the SB and after KBI. Patients were divided into two-dimensional (2D, n=78) and 3D groups (n=72) according to 2D- or 3D-OCT guidance. GW recrossing position, jailing configuration of the stent over the SB (divided into Link-connecting type: stent link connecting to the carina and Link-free type: no stent link at the carina) and stent apposition were compared between the groups. RESULTS: Distal GW recrossing was achieved in 75.6% and 91.7% in the 2D and 3D groups, respectively (P=0.004). Compared with the 2D group, the incidence of incomplete stent apposition (ISA) toward the SB in the 3D group tended to be lower in the whole cohort (14.5±13.6% vs 10.0±9.0%, P=0.077), and was significantly lower in left main trunk bifurcations (18.7±12.8% vs 10.3±8.9%, P=0.014). Independent contributors to ISA were the Link-connecting type (β 0.089, P<0.001), distal GW recrossing (β -0.078, P=0.001), and age (β -0.0020, P=0.012). CONCLUSION: Optimal GW recrossing under 3D-OCT guidance is feasible and improves stent apposition, which may lead to a better clinical outcome in the treatment of bifurcation lesions.