Literature DB >> 29029178

Expansion of Viral Load Testing and the Potential Impact on Human Immunodeficiency Virus Drug Resistance.

Helen M Chun1, Yaa F Obeng-Aduasare2, Laura N Broyles1, Dennis Ellenberger1.   

Abstract

Increasing the volume, strengthening the quality, and proactively using data of human immunodeficiency virus (HIV) load testing are pivotal to limiting the threat of HIV drug resistance (HIVDR) accumulation,and allow for optimal case-based HIVDR surveillance. Triangulation of viral load (VL) and HIVDR testing data could be pursued to answer key questions and translate data and results for program and public policy. Identification of virologic failure and early management mitigates the greater risk of HIVDR. Routine VL monitoring and evaluation systems are necessary, and countries should consider reviewing system requirements, structural needs, and procedural and technical factors for the entire VL cascade, with special emphasis on post-test result use. Published by Oxford University Press for the Infectious Diseases Society of America 2017. This work is written by (a) US Government employee(s) and is in the public domain in the US.

Entities:  

Keywords:  human immunodeficiency virus (HIV) drug resistance; viral load; virologic failure

Mesh：

Year:  2017        PMID： 29029178      PMCID： PMC5745574          DOI： 10.1093/infdis/jix404

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  22 in total

1.  HIV-1 drug resistance in antiretroviral-naive individuals in sub-Saharan Africa after rollout of antiretroviral therapy: a multicentre observational study.

Authors:  Raph L Hamers; Carole L Wallis; Cissy Kityo; Margaret Siwale; Kishor Mandaliya; Francesca Conradie; Mariette E Botes; Maureen Wellington; Akin Osibogun; Kim C E Sigaloff; Immaculate Nankya; Rob Schuurman; Ferdinand W Wit; Wendy S Stevens; Michèle van Vugt; Tobias F Rinke de Wit
Journal:  Lancet Infect Dis       Date:  2011-07-27       Impact factor: 25.071

2.  Risk of virological failure in HIV-1-infected patients experiencing low-level viraemia under active antiretroviral therapy (ANRS C03 cohort study).

Authors:  Marie-Anne Vandenhende; Adélaïde Perrier; Fabrice Bonnet; Estibaliz Lazaro; Charles Cazanave; Sandrine Reigadas; Geneviève Chêne; Philippe Morlat
Journal:  Antivir Ther       Date:  2015-03-04

3.  Unnecessary antiretroviral treatment switches and accumulation of HIV resistance mutations; two arguments for viral load monitoring in Africa.

Authors:  Kim C E Sigaloff; Raph L Hamers; Carole L Wallis; Cissy Kityo; Margaret Siwale; Prudence Ive; Mariette E Botes; Kishor Mandaliya; Maureen Wellington; Akin Osibogun; Wendy S Stevens; Michèle van Vugt; Tobias F Rinke de Wit
Journal:  J Acquir Immune Defic Syndr       Date:  2011-09-01       Impact factor: 3.731

4.  Scaling-up health information systems to improve HIV treatment: An assessment of initial patient monitoring systems in Mozambique.

Authors:  Mindy Hochgesang; Sophia Zamudio-Haas; Lissa Moran; Leopoldo Nhampossa; Laura Packel; Hannah Leslie; Janise Richards; Starley B Shade
Journal:  Int J Med Inform       Date:  2016-11-10       Impact factor: 4.046

5.  Accuracy of WHO CD4 cell count criteria for virological failure of antiretroviral therapy.

Authors:  Olivia Keiser; Patrick MacPhail; Andrew Boulle; Robin Wood; Mauro Schechter; François Dabis; Eduardo Sprinz; Matthias Egger
Journal:  Trop Med Int Health       Date:  2009-07-14       Impact factor: 2.622

6.  Evolution of drug resistance in HIV-infected patients remaining on a virologically failing combination antiretroviral therapy regimen.

Authors:  Alessandro Cozzi-Lepri; Andrew N Phillips; Lidia Ruiz; Bonaventura Clotet; Clive Loveday; Jesper Kjaer; Helene Mens; Nathan Clumeck; Ludmila Viksna; Francisco Antunes; Ladislav Machala; Jens D Lundgren
Journal:  AIDS       Date:  2007-03-30       Impact factor: 4.177

7.  Impact of low-level-viremia on HIV-1 drug-resistance evolution among antiretroviral treated-patients.

Authors:  Constance Delaugerre; Sébastien Gallien; Philippe Flandre; Dominique Mathez; Rishma Amarsy; Samuel Ferret; Julie Timsit; Jean-Michel Molina; Pierre de Truchis
Journal:  PLoS One       Date:  2012-05-10       Impact factor: 3.240

8.  Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: a global collaborative study and meta-regression analysis.

Authors:  Ravindra K Gupta; Michael R Jordan; Binta J Sultan; Andrew Hill; Daniel H J Davis; John Gregson; Anthony W Sawyer; Raph L Hamers; Nicaise Ndembi; Deenan Pillay; Silvia Bertagnolio
Journal:  Lancet       Date:  2012-07-23       Impact factor: 79.321

9.  Impact of HIV Drug Resistance on HIV/AIDS-Associated Mortality, New Infections, and Antiretroviral Therapy Program Costs in Sub-Saharan Africa.

Authors:  Andrew N Phillips; John Stover; Valentina Cambiano; Fumiyo Nakagawa; Michael R Jordan; Deenan Pillay; Meg Doherty; Paul Revill; Silvia Bertagnolio
Journal:  J Infect Dis       Date:  2017-05-01       Impact factor: 5.226

Review 10.  Challenges and opportunities for the implementation of virological testing in resource-limited settings.

Authors:  Teri Roberts; Helen Bygrave; Emmanuel Fajardo; Nathan Ford
Journal:  J Int AIDS Soc       Date:  2012-10-09       Impact factor: 5.396
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  3 in total

1.  Access to HIV Viral Load Testing and Antiretroviral Therapy Switch Practices: A Multicountry Prospective Cohort Study in Sub-Saharan Africa.

Authors:  Pascale Ondoa; Andrea A Kim; T Sonia Boender; Guoqing Zhang; Stefanie Kroeze; Jeffrey Wiener; Tobias Rinke de Wit; John Nkengasong
Journal:  AIDS Res Hum Retroviruses       Date:  2020-08-27       Impact factor: 2.205

2.  Risk factors for delayed viral suppression on first-line antiretroviral therapy among persons living with HIV in Haiti, 2013-2017.

Authors:  Shannan N Rich; Robert L Cook; Lusine Yaghjyan; Kesner Francois; Nancy Puttkammer; Ermane Robin; Jungjun Bae; Nadjy Joseph; Luisa Pessoa-Brandão; Chris Delcher
Journal:  PLoS One       Date:  2020-10-29       Impact factor: 3.240

3.  Impact of the frequency of plasma viral load monitoring on treatment outcomes among children with perinatally acquired HIV.

Authors:  Tavitiya Sudjaritruk; David C Boettiger; Lam Van Nguyen; Thahira J Mohamed; Dewi K Wati; Torsak Bunupuradah; Rawiwan Hansudewechakul; Penh S Ly; Pagakrong Lumbiganon; Revathy A Nallusamy; Moy S Fong; Kulkanya Chokephaibulkit; Nik K Nik Yusoff; Khanh H Truong; Viet C Do; Annette H Sohn; Virat Sirisanthana
Journal:  J Int AIDS Soc       Date:  2019-06       Impact factor: 5.396
  3 in total

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