Christopher L Hager1, Mahmoud A Ghannoum. 1. Center for Medical Mycology, Case Western Reserve University, and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Abstract
PURPOSE OF REVIEW: There are a limited number of studies investigating the association between the microbiome and HIV. Although the majority of these published investigations have focused on the role of the bacterial community (bacteriome) in this setting, a handful of studies have also characterized the role of the mycobiome in HIV-infected individuals. This review will summarize the most recent reports pertaining to the role of the fungal community in HIV. RECENT FINDINGS: Differences in the composition of the oral and respiratory mycobiome in HIV-infected individuals compared with uninfected individuals have been reported. SUMMARY: Our review shows that studies investigating the role of the mycobiome in the setting of HIV are severely lacking. With recent advances in our understanding of the composition of the human microbiome, investigations into the role of the bacteria and fungus comprising the overall microbiota and how the two interact to influence each other and the host is crucial.
PURPOSE OF REVIEW: There are a limited number of studies investigating the association between the microbiome and HIV. Although the majority of these published investigations have focused on the role of the bacterial community (bacteriome) in this setting, a handful of studies have also characterized the role of the mycobiome in HIV-infected individuals. This review will summarize the most recent reports pertaining to the role of the fungal community in HIV. RECENT FINDINGS: Differences in the composition of the oral and respiratory mycobiome in HIV-infected individuals compared with uninfected individuals have been reported. SUMMARY: Our review shows that studies investigating the role of the mycobiome in the setting of HIV are severely lacking. With recent advances in our understanding of the composition of the human microbiome, investigations into the role of the bacteria and fungus comprising the overall microbiota and how the two interact to influence each other and the host is crucial.
Authors: Lijia Cui; Lorrie Lucht; Laura Tipton; Matthew B Rogers; Adam Fitch; Cathy Kessinger; Danielle Camp; Lawrence Kingsley; Nicolas Leo; Ruth M Greenblatt; Serena Fong; Stephen Stone; John C Dermand; Eric C Kleerup; Laurence Huang; Alison Morris; Elodie Ghedin Journal: Am J Respir Crit Care Med Date: 2015-04-15 Impact factor: 21.405
Authors: Pranab K Mukherjee; Jyotsna Chandra; Mauricio Retuerto; Masoumeh Sikaroodi; Robert E Brown; Richard Jurevic; Robert A Salata; Michael M Lederman; Patrick M Gillevet; Mahmoud A Ghannoum Journal: PLoS Pathog Date: 2014-03-13 Impact factor: 6.823
Authors: Alexandra M Ortiz; Jacob K Flynn; Sarah R DiNapoli; Ivan Vujkovic-Cvijin; Carly E Starke; Stephen H Lai; MacKenzie E Long; Ornella Sortino; Carol L Vinton; Joseph C Mudd; Leslie Johnston; Kathleen Busman-Sahay; Yasmine Belkaid; Jacob D Estes; Jason M Brenchley Journal: Nat Med Date: 2018-07-30 Impact factor: 53.440
Authors: Camila Stofella Sodré; Paulo Matheus Guerra Rodrigues; Mayra Stambovsky Vieira; Alexandre Marques Paes da Silva; Lucio Souza Gonçalves; Marcia Gonçalves Ribeiro; Dennis de Carvalho Ferreira Journal: J Oral Microbiol Date: 2020-08-17 Impact factor: 5.474