Literature DB >> 29028208

Tunable and Lightweight On-Chip Event Detection for Implantable Bladder Pressure Monitoring Devices.

Robert Karam, Steve J A Majerus, Dennis J Bourbeau, Margot S Damaser, Swarup Bhunia.   

Abstract

Lower urinary tract dysfunctions, such as urinary incontinence and overactive bladder, are conditions that greatly affect the quality of life for millions of individuals worldwide. For those with more complex pathophysiologies, diagnosis of these conditions often requires a urodynamics study, providing physicians with a snapshot view of bladder mechanics. Recent advancements in implantable bladder pressure monitors and advanced data analysis techniques have made diagnosis through chronic monitoring a promising prospect. However, implants targeted at treatment must remain in the bladder for long periods of time, making minimizing power consumption a primary design objective. Currently, much of the typical implant's power draw is due to data transmission. Previous work has demonstrated an adaptive rate transmission technique to reduce power consumption. However, the ultimate reduction in power consumption can only be attained when the device does not transmit bladder pressure samples, but rather bladder events. In this paper, we present an algorithm and circuit level implementation for on-chip bladder pressure data compression and event detection. It is designed to be a complete, tunable, and lightweight diagnosis and treatment framework for bladder pressure monitoring implants, capable of selectively transmitting compressed bladder pressure data with tunable quality, "snapshots" of significant bladder events, or simply indicate events occurred for the highest energy efficiency. The design aims to minimize area through resource reuse, leading to a total area of 1.75 , and employs advanced VLSI techniques for power reduction. With compression and event detection enabled, the design consumes roughly 2.6 nW in TSMC technology. With only event detection, this reduces to 2.1 nW, making this approach ideal for long-life implantable bladder pressure monitoring devices.

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Mesh:

Year:  2017        PMID: 29028208      PMCID: PMC6944980          DOI: 10.1109/TBCAS.2017.2748981

Source DB:  PubMed          Journal:  IEEE Trans Biomed Circuits Syst        ISSN: 1932-4545            Impact factor:   3.833


  15 in total

1.  Detecting the onset of urinary bladder contractions using an implantable pressure sensor.

Authors:  J Melgaard; N J M Rijkhoff
Journal:  IEEE Trans Neural Syst Rehabil Eng       Date:  2011-10-13       Impact factor: 3.802

2.  Real-time, autonomous bladder event classification and closed-loop control from single-channel pressure data.

Authors:  Robert Karam; Swarup Bhunia; Steve Majerus; Steven W Brose; Margot S Damaser; Dennis Bourbeau
Journal:  Conf Proc IEEE Eng Med Biol Soc       Date:  2016-08

3.  Estimation of bladder volume from afferent neural activity.

Authors:  Arnaldo Mendez; Mohamad Sawan; Tomonori Minagawa; Jean-Jacques Wyndaele
Journal:  IEEE Trans Neural Syst Rehabil Eng       Date:  2013-06-10       Impact factor: 3.802

4.  A Mini-Invasive Long-Term Bladder Urine Pressure Measurement ASIC and System.

Authors: 
Journal:  IEEE Trans Biomed Circuits Syst       Date:  2008-03       Impact factor: 3.833

5.  Design and fabrication of a low cost implantable bladder pressure monitor.

Authors:  F Axisa; P Jourand; E Lippens; M Rymarczyk-Machal; N De Smet; E Schacht; J Vanfleteren; R Puers; R Cornelissen
Journal:  Conf Proc IEEE Eng Med Biol Soc       Date:  2009

6.  International group seeks to dispel incontinence "taboo".

Authors:  R Voelker
Journal:  JAMA       Date:  1998-09-16       Impact factor: 56.272

7.  Extramural ambulatory urodynamic monitoring during natural filling and normal daily activities: evaluation of 100 patients.

Authors:  E S van Waalwijk van Doorn; A Remmers; R A Janknegt
Journal:  J Urol       Date:  1991-07       Impact factor: 7.450

8.  [Prediction of overactive bladder treatment outcome by using long-term urodynamics].

Authors:  S Wille; D Tenholte; O A Cornely; N Muthen; U-H Engelmann; J Mehner; O Eminaga; J Herden; P Schumacher; J Paas
Journal:  Urologe A       Date:  2014-12       Impact factor: 0.639

9.  Multielectrode array recordings of bladder and perineal primary afferent activity from the sacral dorsal root ganglia.

Authors:  Tim M Bruns; Robert A Gaunt; Douglas J Weber
Journal:  J Neural Eng       Date:  2011-08-30       Impact factor: 5.379

10.  Suburothelial Bladder Contraction Detection with Implanted Pressure Sensor.

Authors:  Steve J A Majerus; Paul C Fletter; Elizabeth K Ferry; Hui Zhu; Kenneth J Gustafson; Margot S Damaser
Journal:  PLoS One       Date:  2017-01-06       Impact factor: 3.240

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  1 in total

1.  Feasibility of Real-Time Conditional Sacral Neuromodulation Using Wireless Bladder Pressure Sensor.

Authors:  Steve J A Majerus; Sarah J Offutt; Thaddeus S Brink; Vincent Vasoli; Ian Mcadams; Margot S Damaser; Lance Zirpel
Journal:  IEEE Trans Neural Syst Rehabil Eng       Date:  2021-10-13       Impact factor: 4.528

  1 in total

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