Literature DB >> 2902740

Immunolocalization of dipeptidyl aminopeptidase (DAP IV) in the developing human brain.

H G Bernstein1, E Schön, S Ansorge, I Röse, A Dorn.   

Abstract

By means of immunohistochemical techniques we have investigated the presence of dipeptidyl aminopeptidase IV immunoreactivity in brain material derived from human fetuses, newborns and aged persons. It was revealed that the enzyme protein is abundantly present in the immature human CNS. On the contrary the adult human brain contains much less dipeptidyl aminopeptidase immunoreactivity. It is speculated that the enzyme might play an important role in neuronal proliferation and/or differentiation especially with regard to its possible action on certain neuronotrophic peptides (IGF II, growth hormone).

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Year:  1987        PMID： 2902740     DOI： 10.1016/0736-5748(87)90034-7

Source DB:  PubMed          Journal:  Int J Dev Neurosci        ISSN： 0736-5748            Impact factor:   2.457


  9 in total

1.  Fine structure histochemical study of the distribution of dipeptidylpeptidase IV (DPP IV) in the meningeal lamellae of the rat.

Authors:  P Haninec; P Dubovy
Journal:  Experientia       Date:  1988-08-15

Review 2.  GLP-1: Molecular mechanisms and outcomes of a complex signaling system.

Authors:  Nicholas K Smith; Troy A Hackett; Aurelio Galli; Charles R Flynn
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3.  Reduced neuronal co-localisation of nardilysin and the putative alpha-secretases ADAM10 and ADAM17 in Alzheimer's disease and Down syndrome brains.

Authors:  Hans-Gert Bernstein; Rolf Stricker; Uwe Lendeckel; Iris Bertram; Henrik Dobrowolny; Johann Steiner; Bernhard Bogerts; Georg Reiser
Journal:  Age (Dordr)       Date:  2008-08-30

4.  Comparative immunohistochemistry and histochemistry of dipeptidyl peptidase IV in rat organs during development.

Authors:  S Hartel-Schenk; R Gossrau; W Reutter
Journal:  Histochem J       Date:  1990-10

5.  Mass spectrometry-assisted confirmation of the inability of dipeptidyl peptidase-4 to cleave goldfish peptide YY(1-36) and the lack of anorexigenic effects of peptide YY(3-36) in goldfish (Carassius auratus).

Authors:  R Gonzalez; S Unniappan
Journal:  Fish Physiol Biochem       Date:  2015-12-16       Impact factor: 2.794

6.  Common variants at 12q14 and 12q24 are associated with hippocampal volume.

Authors:  Joshua C Bis; Charles DeCarli; Albert Vernon Smith; Fedde van der Lijn; Fabrice Crivello; Myriam Fornage; Stephanie Debette; Joshua M Shulman; Helena Schmidt; Velandai Srikanth; Maaike Schuur; Lei Yu; Seung-Hoan Choi; Sigurdur Sigurdsson; Benjamin F J Verhaaren; Anita L DeStefano; Jean-Charles Lambert; Clifford R Jack; Maksim Struchalin; Jim Stankovich; Carla A Ibrahim-Verbaas; Debra Fleischman; Alex Zijdenbos; Tom den Heijer; Bernard Mazoyer; Laura H Coker; Christian Enzinger; Patrick Danoy; Najaf Amin; Konstantinos Arfanakis; Mark A van Buchem; Renée F A G de Bruijn; Alexa Beiser; Carole Dufouil; Juebin Huang; Margherita Cavalieri; Russell Thomson; Wiro J Niessen; Lori B Chibnik; Gauti K Gislason; Albert Hofman; Aleksandra Pikula; Philippe Amouyel; Kevin B Freeman; Thanh G Phan; Ben A Oostra; Jason L Stein; Sarah E Medland; Alejandro Arias Vasquez; Derrek P Hibar; Margaret J Wright; Barbara Franke; Nicholas G Martin; Paul M Thompson; Michael A Nalls; Andre G Uitterlinden; Rhoda Au; Alexis Elbaz; Richard J Beare; John C van Swieten; Oscar L Lopez; Tamara B Harris; Vincent Chouraki; Monique M B Breteler; Philip L De Jager; James T Becker; Meike W Vernooij; David Knopman; Franz Fazekas; Philip A Wolf; Aad van der Lugt; Vilmundur Gudnason; W T Longstreth; Matthew A Brown; David A Bennett; Cornelia M van Duijn; Thomas H Mosley; Reinhold Schmidt; Christophe Tzourio; Lenore J Launer; M Arfan Ikram; Sudha Seshadri
Journal:  Nat Genet       Date:  2012-04-15       Impact factor: 38.330

7.  Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia.

Authors:  Peter Röhnert; Werner Schmidt; Patrick Emmerlich; Alexander Goihl; Sabine Wrenger; Ute Bank; Karsten Nordhoff; Michael Täger; Siegfried Ansorge; Dirk Reinhold; Frank Striggow
Journal:  J Neuroinflammation       Date:  2012-02-28       Impact factor: 8.322

8.  Glial cell type-specific changes in spinal dipeptidyl peptidase 4 expression and effects of its inhibitors in inflammatory and neuropatic pain.

Authors:  Kornél Király; Márk Kozsurek; Erika Lukácsi; Benjamin Barta; Alán Alpár; Tamás Balázsa; Csaba Fekete; Judit Szabon; Zsuzsanna Helyes; Kata Bölcskei; Valéria Tékus; Zsuzsanna E Tóth; Károly Pap; Gábor Gerber; Zita Puskár
Journal:  Sci Rep       Date:  2018-02-22       Impact factor: 4.379

Review 9.  Coronaviruses and the central nervous system.

Authors:  Susan Morgello
Journal:  J Neurovirol       Date:  2020-07-31       Impact factor: 3.739
  9 in total

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