Literature DB >> 29024114

Iron deficiency among blood donors: experience from the Danish Blood Donor Study and from the Copenhagen ferritin monitoring scheme.

A S Rigas1, O B Pedersen2, K Magnussen3, C Erikstrup4, H Ullum1.   

Abstract

Blood components collected from blood donors are an invaluable part of modern-day medicine. A healthy blood donor population is therefore of paramount importance. The results from the Danish Blood Donor Study (DBDS) indicate that gender, number of previous donations, time since last donation and menopausal status are the strongest predictors of iron deficiency. Only little information on the health effects of iron deficiency in blood donors exits. Possibly, after a standard full blood donation, a temporarily reduced physical performance for women is observed. However, iron deficiency among blood donors is not reflected in a reduced self-perceived mental and physical health. In general, the high proportion of iron-deficient donors can be alleviated either by extending the inter-donation intervals or by guided iron supplementation. The experience from Copenhagen, the Capital Region of Denmark, is that routine ferritin measurements and iron supplementation are feasible and effective ways of reducing the proportion of donors with low haemoglobin levels.
© 2017 British Blood Transfusion Society.

Entities:  

Keywords:  donor; iron deficiency; iron supplementation

Mesh:

Substances:

Year:  2017        PMID: 29024114     DOI: 10.1111/tme.12477

Source DB:  PubMed          Journal:  Transfus Med        ISSN: 0958-7578            Impact factor:   2.019


  8 in total

Review 1.  Iron status of blood donors.

Authors:  Bryan R Spencer; Alan E Mast
Journal:  Curr Opin Hematol       Date:  2022-07-22       Impact factor: 3.218

2.  Long-Term Course of Haemoglobin and Ferritin Values in High-Frequency Donors of Whole Blood and Double Erythrocyte Apheresis.

Authors:  Vildana Pehlic; Thomas Volken; Andreas Holbro; Zuzana Jirout; Beatrice Drexler; Andreas Buser; Laura Infanti
Journal:  Transfus Med Hemother       Date:  2020-08-05       Impact factor: 3.747

3.  DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors.

Authors:  Thomas Folkmann Hansen; Karina Banasik; Christian Erikstrup; Ole Birger Pedersen; David Westergaard; Piotr Jaroslaw Chmura; Kaspar Nielsen; Lise Thørner; Henrik Hjalgrim; Helene Paarup; Margit Anita Hørup Larsen; Mikkel Petersen; Poul Jennum; Steffen Andersen; Mette Nyegaard; Gregor Borut Ernst Jemec; Jes Olesen; Thomas Werge; Pär I Johansson; Erik Sørensen; Søren Brunak; Henrik Ullum; Kristoffer Sølvsten Burgdorf
Journal:  BMJ Open       Date:  2019-06-09       Impact factor: 2.692

4.  The effect of donation activity dwarfs the effect of lifestyle, diet and targeted iron supplementation on blood donor iron stores.

Authors:  Muriel Lobier; Johanna Castrén; Pia Niittymäki; Elina Palokangas; Jukka Partanen; Mikko Arvas
Journal:  PLoS One       Date:  2019-08-13       Impact factor: 3.240

Review 5.  A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis.

Authors:  Steven Bell; Andreas S Rigas; Magnus K Magnusson; Egil Ferkingstad; Elias Allara; Gyda Bjornsdottir; Anna Ramond; Erik Sørensen; Gisli H Halldorsson; Dirk S Paul; Kristoffer S Burgdorf; Hannes P Eggertsson; Joanna M M Howson; Lise W Thørner; Snaedis Kristmundsdottir; William J Astle; Christian Erikstrup; Jon K Sigurdsson; Dragana Vuckovic; Khoa M Dinh; Vinicius Tragante; Praveen Surendran; Ole B Pedersen; Brynjar Vidarsson; Tao Jiang; Helene M Paarup; Pall T Onundarson; Parsa Akbari; Kaspar R Nielsen; Sigrun H Lund; Kristinn Juliusson; Magnus I Magnusson; Michael L Frigge; Asmundur Oddsson; Isleifur Olafsson; Stephen Kaptoge; Henrik Hjalgrim; Gudmundur Runarsson; Angela M Wood; Ingileif Jonsdottir; Thomas F Hansen; Olof Sigurdardottir; Hreinn Stefansson; David Rye; James E Peters; David Westergaard; Hilma Holm; Nicole Soranzo; Karina Banasik; Gudmar Thorleifsson; Willem H Ouwehand; Unnur Thorsteinsdottir; David J Roberts; Patrick Sulem; Adam S Butterworth; Daniel F Gudbjartsson; John Danesh; Søren Brunak; Emanuele Di Angelantonio; Henrik Ullum; Kari Stefansson
Journal:  Commun Biol       Date:  2021-02-03

6.  Comparison of four methods to measure haemoglobin concentrations in whole blood donors (COMPARE): A diagnostic accuracy study.

Authors:  Steven Bell; Michael Sweeting; Anna Ramond; Ryan Chung; Stephen Kaptoge; Matthew Walker; Thomas Bolton; Jennifer Sambrook; Carmel Moore; Amy McMahon; Sarah Fahle; Donna Cullen; Susan Mehenny; Angela M Wood; Jane Armitage; Willem H Ouwehand; Gail Miflin; David J Roberts; John Danesh; Emanuele Di Angelantonio
Journal:  Transfus Med       Date:  2020-12-20       Impact factor: 2.019

7.  The effects of intravenous iron supplementation on fatigue and general health in non-anemic blood donors with iron deficiency: a randomized placebo-controlled superiority trial.

Authors:  Peter Keller; Roland von Känel; Cesar A Hincapié; Bruno R da Costa; Peter Jüni; Tobias E Erlanger; Nicola Andina; Christoph Niederhauser; Bernhard Lämmle; Stefano Fontana
Journal:  Sci Rep       Date:  2020-08-26       Impact factor: 4.379

8.  Longer-term efficiency and safety of increasing the frequency of whole blood donation (INTERVAL): extension study of a randomised trial of 20 757 blood donors.

Authors:  Stephen Kaptoge; Emanuele Di Angelantonio; Carmel Moore; Matthew Walker; Jane Armitage; Willem H Ouwehand; David J Roberts; John Danesh; Simon G Thompson
Journal:  Lancet Haematol       Date:  2019-08-02       Impact factor: 30.153

  8 in total

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