Takashi Kusunoki1,2, Jiro Takeuchi3, Takeshi Morimoto4, Mio Sakuma4, Takahiro Yasumi2, Ryuta Nishikomori2, Akane Higashi5, Toshio Heike2. 1. Department of Pediatrics, Shiga Medical Center for Children, Shiga, Japan. 2. Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan. 3. Kyoto University Health Service, Kyoto, Japan. 4. Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan. 5. Division of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto, Japan.
Abstract
BACKGROUND: Previous studies have shown that dietary pattern is associated with allergy prevention. METHODS: We conducted a prospective cohort study on all primary schools in Omihachiman City, Shiga Prefecture, Japan. Questionnaires regarding allergic symptoms and diet were distributed to the parents of all 759 7-year-old schoolchildren for 4 consecutive years, from 2011 to 2014. Specific immunoglobulin E to inhalant allergens was measured at 10 years of age. Participants were then categorized as low, medium, or high intake during the study period for four food groups (fruits, vegetables, fish, and beans). Logistic regression analysis was performed to estimate odds ratios and 95% confidence intervals. RESULTS: A total of 520 children (68.5%) whose parents responded to the questionnaires all 4 years were included in the analysis. The prevalence of asthma, rhinitis, and any allergic symptoms at age 10 was significantly decreased with increases in fruit intake. In addition, the onset of any allergic symptoms during the study period was significantly decreased with increases in fruit intake (33.3%, 28.3%, and 14.3% in children with low, medium, and high fruit intake, respectively; P for trend =.01). The sensitization rate to ragweed at age 10 was significantly decreased with increases in fruit intake (P for trend =.046). No significant effect was observed for the other three food groups, except for the association between fish intake and new-onset asthma symptoms. CONCLUSIONS: These findings suggest that higher intake of fruit can help prevent respiratory allergic symptoms in schoolchildren.
BACKGROUND: Previous studies have shown that dietary pattern is associated with allergy prevention. METHODS: We conducted a prospective cohort study on all primary schools in Omihachiman City, Shiga Prefecture, Japan. Questionnaires regarding allergic symptoms and diet were distributed to the parents of all 759 7-year-old schoolchildren for 4 consecutive years, from 2011 to 2014. Specific immunoglobulin E to inhalant allergens was measured at 10 years of age. Participants were then categorized as low, medium, or high intake during the study period for four food groups (fruits, vegetables, fish, and beans). Logistic regression analysis was performed to estimate odds ratios and 95% confidence intervals. RESULTS: A total of 520 children (68.5%) whose parents responded to the questionnaires all 4 years were included in the analysis. The prevalence of asthma, rhinitis, and any allergic symptoms at age 10 was significantly decreased with increases in fruit intake. In addition, the onset of any allergic symptoms during the study period was significantly decreased with increases in fruit intake (33.3%, 28.3%, and 14.3% in children with low, medium, and high fruit intake, respectively; P for trend =.01). The sensitization rate to ragweed at age 10 was significantly decreased with increases in fruit intake (P for trend =.046). No significant effect was observed for the other three food groups, except for the association between fish intake and new-onset asthma symptoms. CONCLUSIONS: These findings suggest that higher intake of fruit can help prevent respiratory allergic symptoms in schoolchildren.
Authors: Jelle Folkerts; Ralph Stadhouders; Frank A Redegeld; See-Ying Tam; Rudi W Hendriks; Stephen J Galli; Marcus Maurer Journal: Front Immunol Date: 2018-05-29 Impact factor: 7.561
Authors: George Antonogeorgos; Kostas N Priftis; Demosthenes B Panagiotakos; Philippa Ellwood; Luis García-Marcos; Evangelia Liakou; Alexandra Koutsokera; Pavlos Drakontaeidis; Marina Thanasia; Maria Mandrapylia; Konstantinos Douros Journal: Children (Basel) Date: 2021-04-16