Literature DB >> 29024

Determination of the metabolites of bezitramide in urine. II. The basic metabolite.

H H van Rooij, C Soe-Agnie.   

Abstract

A high-performance liquid chromatographic method for the determination of low levels (less than 1 microgram/ml) of the basic metabolite of bezitramide, 1-(4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one, in human urine is described. Special attention is given to the separation from the basic metabolite of droperidol, a drug frequently co-administered with bezitramide.

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Year:  1978        PMID: 29024     DOI: 10.1016/s0021-9673(00)83139-8

Source DB:  PubMed          Journal:  J Chromatogr


  1 in total

1.  Pharmacokinetics of the oral narcotic analgesic bezitramide and preliminary observations on its effect on experimentally induced pain.

Authors:  D K Meijer; G Hovinga; A Versluis; J Bröring; K van Aken; F Moolenaar; H Wesseling
Journal:  Eur J Clin Pharmacol       Date:  1984       Impact factor: 2.953

  1 in total

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