Literature DB >> 29022075

A negative answer to a conjecture arising in the study of selection-migration models in population genetics.

Elisa Sovrano1.   

Abstract

We deal with the study of the evolution of the allelic frequencies, at a single locus, for a population distributed continuously over a bounded habitat. We consider evolution which occurs under the joint action of selection and arbitrary migration, that is independent of genotype, in absence of mutation and random drift. The focus is on a conjecture, that was raised up in literature of population genetics, about the possible uniqueness of polymorphic equilibria, which are known as clines, under particular circumstances. We study the number of these equilibria, making use of topological tools, and we give a negative answer to that question by means of two examples. Indeed, we provide numerical evidence of multiplicity of positive solutions for two different Neumann problems satisfying the requests of the conjecture.

Keywords:  Cline; Indefinite weight; Migration; Neumann problem; Polymorphism; Selection

Mesh:

Year:  2017        PMID: 29022075     DOI: 10.1007/s00285-017-1185-7

Source DB:  PubMed          Journal:  J Math Biol        ISSN: 0303-6812            Impact factor:   2.259


  7 in total

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Authors:  T Nagylaki
Journal:  Genetics       Date:  1978-04       Impact factor: 4.562

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Authors:  J B S HALDANE
Journal:  J Genet       Date:  1948-01       Impact factor: 1.166

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Authors:  R A FISHER
Journal:  Biometrics       Date:  1950-12       Impact factor: 2.571

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Authors:  T Nagylaki
Journal:  J Math Biol       Date:  1996       Impact factor: 2.259

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Authors:  T Nagylaki
Journal:  Genetics       Date:  1976-08       Impact factor: 4.562

6.  Gene flow and selection in a cline.

Authors:  M Slatkin
Journal:  Genetics       Date:  1973-12       Impact factor: 4.562

7.  Conditions for the existence of clines.

Authors:  T Nagylaki
Journal:  Genetics       Date:  1975-07       Impact factor: 4.562

  7 in total

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