INTRODUCTION: Cryptococcosis is an opportunistic fungal infection whose etiology is Cryptococcus neofromans / C. gattii, complex which affects immunocompromised patients mainly. Meningeal infection is one of the most common presentations, but cerebellar affection is rare. CASE DESCRIPTION: Male patient with 65 old years, from an area of subtropical climate with chronic exposure to poultry, without pathological antecedents, who presented clinical picture consistent with headache, fever, seizures and altered mental status. CLINICAL FINDINGS AND DIAGNOSTIC METHODS: Initially without menigeal signs or intracranial hypertension and normal neurological examination. Later, the patient developed ataxia, dysdiadochokinesia and limb loss. By lumbar punction and image of nuclear magnetic resonance (NMR) cerebellitis cryptococcal was diagnosticated. TREATMENT: Antifungal therapy with amphotericin B and fluconazole was performed, however the patient died. CLINICAL RELEVANCE: The cryptococcosis has different presentations, it´s a disease whose incidence has been increasing since the advent of the HIV / AIDS pandemy, however the commitment of the encephalic parenchyma and in particular the cerebellum is considered rare. In this way we are facing the first case of cryptococcal cerebellitis in our midst.
INTRODUCTION:Cryptococcosis is an opportunistic fungal infection whose etiology is Cryptococcus neofromans / C. gattii, complex which affects immunocompromised patients mainly. Meningeal infection is one of the most common presentations, but cerebellar affection is rare. CASE DESCRIPTION: Male patient with 65 old years, from an area of subtropical climate with chronic exposure to poultry, without pathological antecedents, who presented clinical picture consistent with headache, fever, seizures and altered mental status. CLINICAL FINDINGS AND DIAGNOSTIC METHODS: Initially without menigeal signs or intracranial hypertension and normal neurological examination. Later, the patient developed ataxia, dysdiadochokinesia and limb loss. By lumbar punction and image of nuclear magnetic resonance (NMR) cerebellitis cryptococcal was diagnosticated. TREATMENT: Antifungal therapy with amphotericin B and fluconazole was performed, however the patient died. CLINICAL RELEVANCE: The cryptococcosis has different presentations, it´s a disease whose incidence has been increasing since the advent of the HIV / AIDS pandemy, however the commitment of the encephalic parenchyma and in particular the cerebellum is considered rare. In this way we are facing the first case of cryptococcal cerebellitis in our midst.
Authors: Valter José Sillero-Filho; Arthur Borges Martins de Souza; Rafael Pereira Vaitsman; Rodrigo Ayres de Morais; Pedro de Oliveira Coutinho; Renata Lengruber; José Massoud Salame; José Fernando Guedes-Corrêa; Paulo Roberto Louzada Journal: Arq Neuropsiquiatr Date: 2009-06 Impact factor: 1.420
Authors: Sharon C-A Chen; Monica A Slavin; Christopher H Heath; E Geoffrey Playford; Karen Byth; Deborah Marriott; Sarah E Kidd; Narin Bak; Bart Currie; Krispin Hajkowicz; Tony M Korman; William J H McBride; Wieland Meyer; Ronan Murray; Tania C Sorrell Journal: Clin Infect Dis Date: 2012-06-05 Impact factor: 9.079
Authors: Benjamin J Park; Kathleen A Wannemuehler; Barbara J Marston; Nelesh Govender; Peter G Pappas; Tom M Chiller Journal: AIDS Date: 2009-02-20 Impact factor: 4.177