Literature DB >> 29021086

Genomic characterization of an extensively drug-resistant KPC-2-producing Klebsiella pneumoniae ST855 (CC258) only susceptible to ceftazidime-avibactam isolated in Brazil.

Caio Augusto Martins Aires1, Michael J Rybak2, Juwon Yim2, Polyana Silva Pereira1, Cláudio M Rocha-de-Souza1, Rodolpho Mattos Albano3, Valdelucia Oliveira Cavalcanti4, Ana Paula D'Alincourt Carvalho-Assef1, Marisa Zenaide Ribeiro Gomes1, Marise Dutra Asensi5.   

Abstract

In this study, we describe the genetic features of an XDR KPC-2-producing Klebsiella pneumoniae isolate by using whole-genome sequencing, its clinical-epidemiological context and susceptibility against antimicrobial combinations. The isolate belongs to clonal complex 258 and harbors several acquired genes and mutations associated with antimicrobial resistance.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Colistin resistance; Extensively drug-resistant; KPC-2; Klebsiella pneumoniae; XDR

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Year:  2017        PMID： 29021086     DOI： 10.1016/j.diagmicrobio.2017.08.017

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  1 in total

1.  Characterization of multidrug-resistant and virulent Klebsiella pneumoniae strains belonging to the high-risk clonal group 258 (CG258) isolated from inpatients in northeastern Brazil.

Authors:  Rafael Nakamura-Silva; Mariana Oliveira-Silva; João Pedro Rueda Furlan; Eliana Guedes Stehling; Carlos Eduardo Saraiva Miranda; André Pitondo-Silva
Journal:  Arch Microbiol       Date:  2021-06-10       Impact factor: 2.552
  1 in total

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