Ruffo de Freitas1,2, Rodrigo Disconzi Nunes1, Edesio Martins3, Maria Paula Curado4,5, Nilceana Maya Aires Freitas2, Leonardo Ribeiro Soares1, José Carlos Oliveira3. 1. - Federal University of Goiás (HC/UFG), Mastology Program, Clinics Hospital, Goiânia, GO, Brazil. 2. - Goiás Association to Cancer Combat (ACCG), Araújo Jorge Hospital, Goiânia, GO, Brazil. 3. - Goiás Association to Cancer Combat (ACCG), Goiânia Population-based Cancer Registry, Goiânia, GO, Brazil. 4. - International Prevention Research Institute (iPRI), Senior Research, Lyon, Auvergne-Rhône-Alpes, France. 5. - AC Camargo Cancer Center, AC Camargo Hospital, São Paulo, SP, Brazil.
Abstract
OBJECTIVE: to analyze the overall survival and prognostic factors of women with breast cancer in the city of Goiânia. METHODS: this is a retrospective, cross-sectional, observational study that included women with malignant neoplasms of the breast identified by the Goiânia Population-based Cancer Registry. The variables studied were age at diagnosis, tumor size, staging, axillary lymph node involvement, tumor grade, disease extent, hormone receptors, and c-erb-B2 oncoprotein. We performed overall survival analyzes of five and ten years. RESULTS: we included 2,273 patients in the study, with an overall survival of 72.1% in five years and 57.8% in ten years. In the multivariate analysis adjusted for tumor size, the factors that influenced the prognosis were axillary lymph nodes, histological grade, progesterone receptor, c erb B2, T staging and disease extension. CONCLUSION: overall survival in ten years is below that observed in other countries, and possibly reflects what happens with the majority of the Brazilian population. The prognostic factors found in this population follow the same international patterns.
OBJECTIVE: to analyze the overall survival and prognostic factors of women with breast cancer in the city of Goiânia. METHODS: this is a retrospective, cross-sectional, observational study that included women with malignant neoplasms of the breast identified by the Goiânia Population-based Cancer Registry. The variables studied were age at diagnosis, tumor size, staging, axillary lymph node involvement, tumor grade, disease extent, hormone receptors, and c-erb-B2 oncoprotein. We performed overall survival analyzes of five and ten years. RESULTS: we included 2,273 patients in the study, with an overall survival of 72.1% in five years and 57.8% in ten years. In the multivariate analysis adjusted for tumor size, the factors that influenced the prognosis were axillary lymph nodes, histological grade, progesterone receptor, c erb B2, T staging and disease extension. CONCLUSION: overall survival in ten years is below that observed in other countries, and possibly reflects what happens with the majority of the Brazilian population. The prognostic factors found in this population follow the same international patterns.
Authors: Leonardo R Soares; Ruffo Freitas-Junior; Maria P Curado; Regis R Paulinelli; Edesio Martins; José C Oliveira Journal: JCO Glob Oncol Date: 2020-04
Authors: Adriane Dórea Marques; Alex Rodrigues Moura; Evânia Curvelo Hora; Érika de Abreu Costa Brito; Leonardo Souto Oliviera; Ionara Rodrigues Feitosa; Flavia Fernandes Freitas; Marcela Sampaio Lima; Íkaro Daniel de Carvalho Barreto; Marceli Oliveira Santos; Angela Maria da Silva; Carlos Anselmo Lima Journal: PLoS One Date: 2022-02-03 Impact factor: 3.240