| Literature DB >> 29018980 |
Simone Tosoni1, Vincenzo Tarzia2, Andrea Colli2, Gino Gerosa2, Andrea Bagno3.
Abstract
The formation of thrombotic deposits affects the functionality of mechanical prosthetic heart valves; as a consequence, mechanical valves thrombosis needs early diagnosis to prevent thromboembolic events. This paper compares the acoustic signals produced by two commercial bileaflet mechanical heart valves in the closing phase to detect the presence of thrombi. The closing sounds were recorded in vitro by means of a phonocardiographic device under different hydrodynamic conditions. Thrombotic deposits of different weight and shape were applied onto the valve leaflet and the annular housing, until the movement of one leaflet was completely blocked. From the acoustic signals, the corresponding spectra were calculated and four diagnostic frequency bands were identified: their comparison allowed detecting malfunctioning valves because of the presence of thrombotic formations.Entities:
Keywords: Heart valve thrombosis; Mechanical heart valve; Phonocardiography
Mesh:
Year: 2017 PMID: 29018980 DOI: 10.1007/s10047-017-1002-5
Source DB: PubMed Journal: J Artif Organs ISSN: 1434-7229 Impact factor: 1.731