Literature DB >> 29018636

Detecting Dementia Through Interactive Computer Avatars.

Hiroki Tanaka1, Hiroyoshi Adachi2, Norimichi Ukita3, Manabu Ikeda4, Hiroaki Kazui4, Takashi Kudo2, Satoshi Nakamura1.   

Abstract

This paper proposes a new approach to automatically detect dementia. Even though some works have detected dementia from speech and language attributes, most have applied detection using picture descriptions, narratives, and cognitive tasks. In this paper, we propose a new computer avatar with spoken dialog functionalities that produces spoken queries based on the mini-mental state examination, the Wechsler memory scale-revised, and other related neuropsychological questions. We recorded the interactive data of spoken dialogues from 29 participants (14 dementia and 15 healthy controls) and extracted various audiovisual features. We tried to predict dementia using audiovisual features and two machine learning algorithms (support vector machines and logistic regression). Here, we show that the support vector machines outperformed logistic regression, and by using the extracted features they classified the participants into two groups with 0.93 detection performance, as measured by the areas under the receiver operating characteristic curve. We also newly identified some contributing features, e.g., gap before speaking, the variations of fundamental frequency, voice quality, and the ratio of smiling. We concluded that our system has the potential to detect dementia through spoken dialog systems and that the system can assist health care workers. In addition, these findings could help medical personnel detect signs of dementia.

Entities:  

Keywords:  Alzheimer’s disease; Dementia; MMSE; computer avatars; spoken dialogue

Year:  2017        PMID: 29018636      PMCID: PMC5630006          DOI: 10.1109/JTEHM.2017.2752152

Source DB:  PubMed          Journal:  IEEE J Transl Eng Health Med        ISSN: 2168-2372            Impact factor:   3.316


  28 in total

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Authors:  J R Crawford; Paul H Garthwaite
Journal:  Neuropsychologia       Date:  2002       Impact factor: 3.139

2.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician.

Authors:  M F Folstein; S E Folstein; P R McHugh
Journal:  J Psychiatr Res       Date:  1975-11       Impact factor: 4.791

3.  Basic principles of ROC analysis.

Authors:  C E Metz
Journal:  Semin Nucl Med       Date:  1978-10       Impact factor: 4.446

Review 4.  Using uh and um in spontaneous speaking.

Authors:  Herbert H Clark; Jean E Fox Tree
Journal:  Cognition       Date:  2002-05

5.  Unobtrusive monitoring of computer interactions to detect cognitive status in elders.

Authors:  Holly Jimison; Misha Pavel; James McKanna; Jesse Pavel
Journal:  IEEE Trans Inf Technol Biomed       Date:  2004-09

6.  Early detection of cognitive impairment in the elderly based on Bayesian mining using speech prosody and cerebral blood flow activation.

Authors:  Shohei Kato; Hidetoshi Endo; Akira Homma; Takuto Sakuma; Keita Watanabe
Journal:  Conf Proc IEEE Eng Med Biol Soc       Date:  2013

7.  Does education level determine the course of cognitive decline?

Authors:  D Leibovici; K Ritchie; B Ledésert; J Touchon
Journal:  Age Ageing       Date:  1996-09       Impact factor: 10.668

Review 8.  Cost-effective recognition and diagnosis of dementia.

Authors:  David S Geldmacher
Journal:  Semin Neurol       Date:  2002-03       Impact factor: 3.420

Review 9.  Language performance in Alzheimer's disease and mild cognitive impairment: a comparative review.

Authors:  Vanessa Taler; Natalie A Phillips
Journal:  J Clin Exp Neuropsychol       Date:  2008-07       Impact factor: 2.475

Review 10.  Innovative diagnostic tools for early detection of Alzheimer's disease.

Authors:  Christoph Laske; Hamid R Sohrabi; Shaun M Frost; Karmele López-de-Ipiña; Peter Garrard; Massimo Buscema; Justin Dauwels; Surjo R Soekadar; Stephan Mueller; Christoph Linnemann; Stephanie A Bridenbaugh; Yogesan Kanagasingam; Ralph N Martins; Sid E O'Bryant
Journal:  Alzheimers Dement       Date:  2014-11-15       Impact factor: 21.566

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  4 in total

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Journal:  J Med Internet Res       Date:  2020-06-05       Impact factor: 5.428

Review 2.  Voice-Based Conversational Agents for the Prevention and Management of Chronic and Mental Health Conditions: Systematic Literature Review.

Authors:  Caterina Bérubé; Theresa Schachner; Roman Keller; Elgar Fleisch; Florian V Wangenheim; Filipe Barata; Tobias Kowatsch
Journal:  J Med Internet Res       Date:  2021-03-29       Impact factor: 5.428

3.  Expressing Personality Through Non-verbal Behaviour in Real-Time Interaction.

Authors:  Maryam Saberi; Steve DiPaola; Ulysses Bernardet
Journal:  Front Psychol       Date:  2021-11-26

4.  Smart integration of sensors, computer vision and knowledge representation for intelligent monitoring and verbal human-computer interaction.

Authors:  Thanassis Mavropoulos; Spyridon Symeonidis; Athina Tsanousa; Panagiotis Giannakeris; Maria Rousi; Eleni Kamateri; Georgios Meditskos; Konstantinos Ioannidis; Stefanos Vrochidis; Ioannis Kompatsiaris
Journal:  J Intell Inf Syst       Date:  2021-06-10       Impact factor: 1.888

  4 in total

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