Literature DB >> 29018167

Inhibition of Small-Conductance Ca2+-Activated K+ Channels: The Long-Awaited Breakthrough for Antiarrhythmic Drug Therapy of Atrial Fibrillation?

Jordi Heijman1, Dobromir Dobrev2.   

Abstract

Entities:  

Keywords:  Editorials; atrial fibrillation; catheter ablation; morbidity; prevalence; stroke

Mesh：

Substances：

Year:  2017        PMID： 29018167      PMCID： PMC5646693          DOI： 10.1161/CIRCEP.117.005776

Source DB:  PubMed          Journal:  Circ Arrhythm Electrophysiol        ISSN： 1941-3084


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  20 in total

1.  Protein kinase CK2 is coassembled with small conductance Ca(2+)-activated K+ channels and regulates channel gating.

Authors:  Wolfgang Bildl; Tim Strassmaier; Henrike Thurm; Jens Andersen; Silke Eble; Dominik Oliver; Marlies Knipper; Matthias Mann; Uwe Schulte; John P Adelman; Bernd Fakler
Journal:  Neuron       Date:  2004-09-16       Impact factor: 17.173

Review 2.  Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression.

Authors:  Jordi Heijman; Niels Voigt; Stanley Nattel; Dobromir Dobrev
Journal:  Circ Res       Date:  2014-04-25       Impact factor: 17.367

3.  2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the Heart Rhythm Society.

Authors:  Craig T January; L Samuel Wann; Joseph S Alpert; Hugh Calkins; Joaquin E Cigarroa; Joseph C Cleveland; Jamie B Conti; Patrick T Ellinor; Michael D Ezekowitz; Michael E Field; Katherine T Murray; Ralph L Sacco; William G Stevenson; Patrick J Tchou; Cynthia M Tracy; Clyde W Yancy
Journal:  Circulation       Date:  2014-03-28       Impact factor: 29.690

4.  EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies: definition, characterization, and clinical implication.

Authors:  Andreas Goette; Jonathan M Kalman; Luis Aguinaga; Joseph Akar; Jose Angel Cabrera; Shih Ann Chen; Sumeet S Chugh; Domenico Corradi; Andre D'Avila; Dobromir Dobrev; Guilherme Fenelon; Mario Gonzalez; Stephane N Hatem; Robert Helm; Gerhard Hindricks; Siew Yen Ho; Brian Hoit; Jose Jalife; Young-Hoon Kim; Gregory Y H Lip; Chang-Sheng Ma; Gregory M Marcus; Katherine Murray; Akihiko Nogami; Prashanthan Sanders; William Uribe; David R Van Wagoner; Stanley Nattel
Journal:  Europace       Date:  2016-07-08       Impact factor: 5.214

Review 5.  Atrial fibrillation: Therapeutic potential of atrial K+ channel blockers.

Authors:  Ursula Ravens; Katja E Odening
Journal:  Pharmacol Ther       Date:  2016-10-12       Impact factor: 12.310

6.  Proarrhythmic effect of blocking the small conductance calcium activated potassium channel in isolated canine left atrium.

Authors:  Chia-Hsiang Hsueh; Po-Cheng Chang; Yu-Cheng Hsieh; Thomas Reher; Peng-Sheng Chen; Shien-Fong Lin
Journal:  Heart Rhythm       Date:  2013-01-30       Impact factor: 6.343

7.  Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation.

Authors:  Ning Li; Valeriy Timofeyev; Dipika Tuteja; Danyan Xu; Ling Lu; Qian Zhang; Zhao Zhang; Anil Singapuri; Trevine R Albert; Amutha V Rajagopal; Chris T Bond; Muthu Periasamy; John Adelman; Nipavan Chiamvimonvat
Journal:  J Physiol       Date:  2009-01-12       Impact factor: 5.182

8.  Small and intermediate conductance Ca(2+)-activated K+ channels confer distinctive patterns of distribution in human tissues and differential cellular localisation in the colon and corpus cavernosum.

Authors:  Mao Xiang Chen; Shelby A Gorman; Bill Benson; Kuljit Singh; J Paul Hieble; Martin C Michel; Simon N Tate; Derek J Trezise
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2004-05-01       Impact factor: 3.000

Review 9.  A roadmap to improve the quality of atrial fibrillation management: proceedings from the fifth Atrial Fibrillation Network/European Heart Rhythm Association consensus conference.

Authors:  Paulus Kirchhof; Günter Breithardt; Jeroen Bax; Gerlinde Benninger; Carina Blomstrom-Lundqvist; Giuseppe Boriani; Axel Brandes; Helen Brown; Martina Brueckmann; Hugh Calkins; Melanie Calvert; Vincent Christoffels; Harry Crijns; Dobromir Dobrev; Patrick Ellinor; Larissa Fabritz; Thomas Fetsch; S Ben Freedman; Andrea Gerth; Andreas Goette; Eduard Guasch; Guido Hack; Laurent Haegeli; Stephane Hatem; Karl Georg Haeusler; Hein Heidbüchel; Jutta Heinrich-Nols; Francoise Hidden-Lucet; Gerd Hindricks; Steen Juul-Möller; Stefan Kääb; Lukas Kappenberger; Stefanie Kespohl; Dipak Kotecha; Deirdre A Lane; Angelika Leute; Thorsten Lewalter; Ralf Meyer; Lluis Mont; Felix Münzel; Michael Nabauer; Jens C Nielsen; Michael Oeff; Jonas Oldgren; Ali Oto; Jonathan P Piccini; Art Pilmeyer; Tatjana Potpara; Ursula Ravens; Holger Reinecke; Thomas Rostock; Joerg Rustige; Irene Savelieva; Renate Schnabel; Ulrich Schotten; Lars Schwichtenberg; Moritz F Sinner; Gerhard Steinbeck; Monika Stoll; Luigi Tavazzi; Sakis Themistoclakis; Hung Fat Tse; Isabelle C Van Gelder; Panagiotis E Vardas; Timo Varpula; Alphons Vincent; David Werring; Stephan Willems; André Ziegler; Gregory Y H Lip; A John Camm
Journal:  Europace       Date:  2015-10-18       Impact factor: 5.214

10.  Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs.

Authors:  Jonas Goldin Diness; Lasse Skibsbye; Rafel Simó-Vicens; Joana Larupa Santos; Pia Lundegaard; Carlotta Citerni; Daniel Rafael Peter Sauter; Sofia Hammami Bomholtz; Jesper Hastrup Svendsen; Søren-Peter Olesen; Ulrik S Sørensen; Thomas Jespersen; Morten Grunnet; Bo Hjorth Bentzen
Journal:  Circ Arrhythm Electrophysiol       Date:  2017-10
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  8 in total

1.  Sex-specific density of ventricular SK currents: is this a general feature of SK channel function?

Authors:  Dobromir Dobrev
Journal:  J Physiol       Date:  2018-07-18       Impact factor: 5.182

2.  Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man.

Authors:  Bo Hjorth Bentzen; Sofia Hammami Bomholtz; Rafel Simó-Vicens; Lasse Folkersen; Lea Abildgaard; Tobias Speerschneider; Kalai Mangai Muthukumarasamy; Nils Edvardsson; Ulrik S Sørensen; Morten Grunnet; Jonas Goldin Diness
Journal:  Front Pharmacol       Date:  2020-05-06       Impact factor: 5.810

3.  Inhibitory Effects of Dronedarone on Small Conductance Calcium Activated Potassium Channels in Patients with Chronic Atrial Fibrillation: Comparison to Amiodarone.

Authors:  Yiyan Yu; Dan Luo; Zhiyi Li; Juan Zhang; Fang Li; Jie Qiao; Fengxu Yu; Miaoling Li
Journal:  Med Sci Monit       Date:  2020-05-29

4.  PKA phosphorylation underlies functional recruitment of sarcolemmal SK2 channels in ventricular myocytes from hypertrophic hearts.

Authors:  Shanna Hamilton; Iuliia Polina; Radmila Terentyeva; Peter Bronk; Tae Yun Kim; Karim Roder; Richard T Clements; Gideon Koren; Bum-Rak Choi; Dmitry Terentyev
Journal:  J Physiol       Date:  2019-03-20       Impact factor: 5.182

5.  Small Conductance Ca2 +-Activated K+ (SK) Channel mRNA Expression in Human Atrial and Ventricular Tissue: Comparison Between Donor, Atrial Fibrillation and Heart Failure Tissue.

Authors:  Elisa Darkow; Thong T Nguyen; Marina Stolina; Fabian A Kari; Constanze Schmidt; Felix Wiedmann; István Baczkó; Peter Kohl; Sridharan Rajamani; Ursula Ravens; Rémi Peyronnet
Journal:  Front Physiol       Date:  2021-04-01       Impact factor: 4.566

6.  Inhibition of Small-Conductance, Ca2+-Activated K+ Current by Ondansetron.

Authors:  Shuai Guo; Zhenhui Chen; Peng-Sheng Chen; Michael Rubart
Journal:  Front Pharmacol       Date:  2021-04-22       Impact factor: 5.810

Review 7.  Antiarrhythmic drugs for atrial fibrillation: Imminent impulses are emerging.

Authors:  Gheorghe-Andrei Dan; Dobromir Dobrev
Journal:  Int J Cardiol Heart Vasc       Date:  2018-09-13

8.  The KCa2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs.

Authors:  Jonas Goldin Diness; Jeppe Egedal Kirchhoff; Tobias Speerschneider; Lea Abildgaard; Nils Edvardsson; Ulrik S Sørensen; Morten Grunnet; Bo Hjorth Bentzen
Journal:  Front Pharmacol       Date:  2020-02-28       Impact factor: 5.810
  8 in total

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