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Literature DB >> 29017785

Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA.

Jana Balintová¹, Anna Simonova¹, Magdalena Białek-Pietras², Agnieszka Olejniczak², Zbigniew J Lesnikowski³, Michal Hocek⁴.

Abstract

5-[(p-Carborane-2-yl)ethynyl]-2'-deoxyuridine 5'-O-triphosphate was synthesized and used as a good substrate in enzymatic construction of carborane-modified DNA or oligonucleotides containing up to 21 carborane moieties in primer extension reactions by DNA polymerases.

Entities: Chemical

Keywords: Carboranes; DNA polymerase; Nucleoside triphosphates; Nucleotides; Oligonucleotides

Mesh：

Substances：

Year: 2017 PMID： 29017785 DOI： 10.1016/j.bmcl.2017.09.064

Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823

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Cited

4 in total

Review 1. DNA Modified with Boron⁻Metal Cluster Complexes [M(C₂B₉H₁₁)₂]-Synthesis, Properties, and Applications.

Authors: Agnieszka B Olejniczak; Barbara Nawrot; Zbigniew J Leśnikowski
Journal: Int J Mol Sci Date: 2018-11-07 Impact factor: 5.923

Review 2. Recent Advances in the Synthesis of High Boron-Loaded Nucleic Acids for BNCT.

Authors: Darya Sergeevna Novopashina; Mariya Alexandrovna Vorobyeva; Alya Venyaminova
Journal: Front Chem Date: 2021-03-15 Impact factor: 5.221

Review 3. Aptamers Chemistry: Chemical Modifications and Conjugation Strategies.

Authors: Fadwa Odeh; Hamdi Nsairat; Walhan Alshaer; Mohammad A Ismail; Ezaldeen Esawi; Baraa Qaqish; Abeer Al Bawab; Said I Ismail
Journal: Molecules Date: 2019-12-18 Impact factor: 4.411

4. Enzymatic synthesis of hypermodified DNA polymers for sequence-specific display of four different hydrophobic groups.

Authors: Marek Ondruš; Veronika Sýkorová; Lucie Bednárová; Radek Pohl; Michal Hocek
Journal: Nucleic Acids Res Date: 2020-12-02 Impact factor: 16.971