Literature DB >> 29017053

Apoptosis, Up the Ante.

Palaniraja Thandapani1, Iannis Aifantis2.   

Abstract

The clinical success of the BH3-mimetic venetoclax has generated increasing interest to target BCL2 family proteins in oncology. In this issue of Cancer Cell, Reyna and colleagues demonstrate the potential of a pharmacological activator of the pro-apoptotic protein BAX to suppress acute myeloid leukemia both alone and together with venetoclax.
Copyright © 2017. Published by Elsevier Inc.

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Year:  2017        PMID： 29017053     DOI： 10.1016/j.ccell.2017.09.009

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  6 in total

1.  Nifuroxazide induces apoptosis, inhibits cell migration and invasion in osteosarcoma.

Authors:  Yi Luo; Anqi Zeng; Aiping Fang; Linjiang Song; Chen Fan; Chenjuan Zeng; Tinghong Ye; Hao Chen; Chongqi Tu; Yongmei Xie
Journal:  Invest New Drugs       Date:  2019-01-25       Impact factor: 3.850

2.  Knockdown of PHGDH potentiates 5-FU cytotoxicity in gastric cancer cells via the Bcl-2/Bax/caspase-3 signaling pathway.

Authors:  Yunli Zhang; Litao Yang; Guangou Dai; Hu Cao
Journal:  Int J Clin Exp Pathol       Date:  2018-12-01

3.  HOXA10 induces BCL2 expression, inhibits apoptosis, and promotes cell proliferation in gastric cancer.

Authors:  Chenlong Song; Yang Han; Huan Luo; Zhiwei Qin; Zhengqian Chen; Yuan Liu; Su Lu; Huimin Sun; Chongzhi Zhou
Journal:  Cancer Med       Date:  2019-07-30       Impact factor: 4.452

4.  Potent USP10/13 antagonist spautin-1 suppresses melanoma growth via ROS-mediated DNA damage and exhibits synergy with cisplatin.

Authors:  Jia Guo; JiangLing Zhang; Long Liang; Nian Liu; Min Qi; Shuang Zhao; Juan Su; Jing Liu; Cong Peng; Xiang Chen; Hong Liu
Journal:  J Cell Mol Med       Date:  2020-03-04       Impact factor: 5.310

5.  The Olive Biophenols Oleuropein and Hydroxytyrosol Selectively Reduce Proliferation, Influence the Cell Cycle, and Induce Apoptosis in Pancreatic Cancer Cells.

Authors:  Chloe D Goldsmith; Danielle R Bond; Helen Jankowski; Judith Weidenhofer; Costas E Stathopoulos; Paul D Roach; Christopher J Scarlett
Journal:  Int J Mol Sci       Date:  2018-07-02       Impact factor: 5.923

6.  Heat-killed Salmonella Typhimurium protects mice against carbon ion radiation.

Authors:  Zebin Liao; Zhe Liu; Zhenyu Gong; Xuguang Hu; Yuanyuan Chen; Kun Cao; Hong Zhang; Lu Gan; Juxiang Chen; Yanyong Yang; Jianming Cai
Journal:  J Int Med Res       Date:  2020-10       Impact factor: 1.671
  6 in total

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