Literature DB >> 29016566

Demographics, Resource Utilization, and Outcomes of Elderly Patients With Chronic Liver Disease Receiving Hospice Care in the United States.

Natsu Fukui1, Pegah Golabi2, Munkhzul Otgonsuren2, Alita Mishra1,2, Chapy Venkatesan1, Zobair M Younossi1,2.   

Abstract

OBJECTIVES: Hospice offers non-curative symptomatic management to improve patients' quality of life, satisfaction, and resource utilization. Hospice enrollment among patients with chronic liver disease (CLD) is not well studied. The aim of tis tudy is to examine the characteristics of Medicare enrollees with CLD, who were discharged to hospice.
METHODS: Medicare patients discharged to hospice between 2010 and 2014 were identified in Medicare Inpatient and Hospice Files. CLDs and other co-morbidities were identified by International Classification of Diseases-ninth revision codes. Generalized linear model was used to estimate regression coefficients with P-values. Logistic regression was used to calculate odds ratios and 95% confidence intervals.
RESULTS: A total of 2,179 CLD patients and 34,986 controls without CLD met the inclusion criteria. Non-alcoholic fatty liver disease, alcoholic liver disease, and hepatitis C virus (HCV) were the most frequent cause of CLD. CLD patients were younger (70 vs. 83 years), more likely to be male (57.7 vs. 39.3%), had longer hospital stay (length of stay, LOS) (19.4 vs. 13.0 days), higher annual charges ($175,000 vs. $109,000), higher 30-day re-hospitalization rates (51.6 vs. 34.2%), and shorter hospice LOS (13.7 vs. 17.7 days) than controls (all P<0.001). Presence of HCV and congestive heart failure were the strongest contributors to increased total annual costs (34% and 31% higher, P<0.001), increased total annual LOS (26% and 43% higher, P<0.001), and increased 30-day readmission risk (2.20 and 2.19 times, respectively).
CONCLUSIONS: Patients with CLD have longer and costly hospitalizations before hospice enrollment as compared with patients without CLD. It was highly likely that these patients were enrolled relatively late, which could potentially lead to less benefit from hospice.

Entities:  

Mesh:

Year:  2017        PMID: 29016566     DOI: 10.1038/ajg.2017.290

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN: 0002-9270            Impact factor:   10.864


  28 in total

1.  Survival of Medicare patients after enrollment in hospice programs.

Authors:  N A Christakis; J J Escarce
Journal:  N Engl J Med       Date:  1996-07-18       Impact factor: 91.245

2.  Quality of life in cirrhosis is related to potentially treatable factors.

Authors:  Iñigo Les; Eduardo Doval; Montserrat Flavià; Carlos Jacas; Guillermo Cárdenas; Rafael Esteban; Jaime Guardia; Juan Córdoba
Journal:  Eur J Gastroenterol Hepatol       Date:  2010-02       Impact factor: 2.566

3.  The impact of liver disease and medical complications on quality of life and psychological distress before and after liver transplantation.

Authors:  M De Bona; P Ponton; M Ermani; R M Iemmolo; A Feltrin; P Boccagni; G Gerunda; R Naccarato; G Rupolo; P Burra
Journal:  J Hepatol       Date:  2000-10       Impact factor: 25.083

4.  Dying trajectory in the last year of life: does cancer trajectory fit other diseases?

Authors:  J M Teno; S Weitzen; M L Fennell; V Mor
Journal:  J Palliat Med       Date:  2001       Impact factor: 2.947

5.  Evaluation of prognostic criteria for determining hospice eligibility in patients with advanced lung, heart, or liver disease. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments.

Authors:  E Fox; K Landrum-McNiff; Z Zhong; N V Dawson; A W Wu; J Lynn
Journal:  JAMA       Date:  1999-11-03       Impact factor: 56.272

6.  Factors in hospice patients' length of stay.

Authors:  T T Frantz; J C Lawrence; P G Somov; M J Somova
Journal:  Am J Hosp Palliat Care       Date:  1999 Mar-Apr       Impact factor: 2.500

7.  Disease-specific patterns of hospice and related healthcare use in an incidence cohort of seriously ill elderly patients.

Authors:  Theodore J Iwashyna; James X Zhang; Nicholas A Christakis
Journal:  J Palliat Med       Date:  2002-08       Impact factor: 2.947

8.  Are physician-derived disease severity indices associated with health-related quality of life in patients with end-stage liver disease?

Authors:  Fasiha Kanwal; Ron D Hays; Amy M Kilbourne; Gareth S Dulai; Ian M Gralnek
Journal:  Am J Gastroenterol       Date:  2004-09       Impact factor: 10.864

9.  The impact of advance care planning on end of life care in elderly patients: randomised controlled trial.

Authors:  Karen M Detering; Andrew D Hancock; Michael C Reade; William Silvester
Journal:  BMJ       Date:  2010-03-23

10.  The health impact of health care on families: a matched cohort study of hospice use by decedents and mortality outcomes in surviving, widowed spouses.

Authors:  Nicholas A Christakis; Theodore J Iwashyna
Journal:  Soc Sci Med       Date:  2003-08       Impact factor: 4.634

View more
  8 in total

1.  The Efficacy of Hospice Care for Terminally Ill Emergency Patients During the Coronavirus 2019 Pandemic.

Authors:  Qing-Ling Wang; Bin-Ru Han; Peng Yue
Journal:  J Multidiscip Healthc       Date:  2022-08-04

Review 2.  Epidemiologic, humanistic and economic burden of hepatocellular carcinoma in the USA: a systematic literature review.

Authors:  Abdalla Aly; Sarah Ronnebaum; Dipen Patel; Yunes Doleh; Fernando Benavente
Journal:  Hepat Oncol       Date:  2020-07-21

3.  Disparities in Mortality and Health Care Utilization for 460,851 Hospitalized Patients with Cirrhosis and Hepatic Encephalopathy.

Authors:  Harry Trieu; Arpan Patel; Christine Wells; Sammy Saab; Edward Wolfgang Lee
Journal:  Dig Dis Sci       Date:  2020-09-14       Impact factor: 3.199

4.  Health Care Utilization and End-of-Life Care Outcomes for Patients With Decompensated Cirrhosis Based on Transplant Candidacy.

Authors:  Nneka N Ufere; Jennifer L Halford; Joshua Caldwell; Min Young Jang; Sunil Bhatt; John Donlan; Janet Ho; Vicki Jackson; Raymond T Chung; Areej El-Jawahri
Journal:  J Pain Symptom Manage       Date:  2019-10-23       Impact factor: 3.612

5.  Acarbose Use and Liver Injury in Diabetic Patients With Severe Renal Insufficiency and Hepatic Diseases: A Propensity Score-Matched Cohort Study.

Authors:  Chia-Ter Chao; Jui Wang; Jenq-Wen Huang; Kuo-Liong Chien
Journal:  Front Pharmacol       Date:  2018-08-07       Impact factor: 5.810

6.  Lowering the upper limit of serum alanine aminotransferase levels may reveal significant liver disease in the elderly.

Authors:  Hemda Schmilovitz-Weiss; Rachel Gingold-Belfer; Alon Grossman; Nidal Issa; Doron Boltin; Yichayaou Beloosesky; Nira Morag Koren; Joseph Meyerovitch; Avraham Weiss
Journal:  PLoS One       Date:  2019-04-11       Impact factor: 3.240

7.  Duration of palliative care before death in international routine practice: a systematic review and meta-analysis.

Authors:  Roberta I Jordan; Matthew J Allsop; Yousuf ElMokhallalati; Catriona E Jackson; Helen L Edwards; Emma J Chapman; Luc Deliens; Michael I Bennett
Journal:  BMC Med       Date:  2020-11-26       Impact factor: 8.775

8.  Hospice care utilisation among elderly patients who died with hepatocellular carcinoma in the United States.

Authors:  Victor de Avila; James M Paik; Leyla de Avila; Linda Henry; Denise Mohess; Alva Roche-Green; Zobair M Younossi
Journal:  JHEP Rep       Date:  2021-01-27
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.