Literature DB >> 29016310

Case Report: A Cluster of Three Leptospirosis Cases in a New York City Abattoir and an Unusual Complication in the Index Case.

Tania Kupferman1, Megan P Coffee2,1, Benjamin J Eckhardt1.   

Abstract

We report the case of a 46-year-old male abattoir worker who developed myalgias, shortness of breath, and irritability 2 weeks after sustaining a laceration to the hand with a knife at work. During his hospital evaluation for septic shock he was noted to be febrile, hypotensive, profoundly jaundiced with aseptic meningitis, and renal failure, and was diagnosed with Leptospirosis interrogans infection confirmed by serum and urine polymerase chain reaction. After standard antibiotic therapy and recovery from severe clinical illness, he developed unilateral orchitis with pyuria secondary to leptospirosis, a well-established complication in the veterinary literature, but of which we offer the first report in humans in the English literature. The case presented was also the index case that uncovered a cluster outbreak of leptospirosis in New York City during the winter of 2016-2017, involving a total of three patients who lived or worked within a block of the abattoir. Two patients survived whereas the third died of pulmonary hemorrhage shortly after seeking medical care.

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Year:  2017        PMID: 29016310      PMCID: PMC5805074          DOI: 10.4269/ajtmh.17-0545

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  6 in total

1.  EXPERIMENTAL LEPTOSPIRA POMONA INFECTION IN BULLS.

Authors:  S D SLEIGHT; O A ATALLAH; D J STEINBAUER
Journal:  Am J Vet Res       Date:  1964-11       Impact factor: 1.156

2.  EXPERIMENTAL LEPTOSPIROSIS IN RAMS.

Authors:  R E SMITH; I M REYNOLDS; G W CLARK
Journal:  Cornell Vet       Date:  1965-07

3.  [On a laboratory Leptospira ballum infection; orchitis as a complication].

Authors:  R KAPPELER; S BARANDUN; H LUTHI; E WIESMANN
Journal:  Schweiz Med Wochenschr       Date:  1961-07-08

Review 4.  Atypical manifestations of leptospirosis.

Authors:  Senaka Rajapakse; Chaturaka Rodrigo; Krishan Balaji; Sumadhya Deepika Fernando
Journal:  Trans R Soc Trop Med Hyg       Date:  2015-03-25       Impact factor: 2.184

Review 5.  High dose corticosteroids in severe leptospirosis: a systematic review.

Authors:  Chaturaka Rodrigo; Nipun Lakshitha de Silva; Ravindi Goonaratne; Keshinie Samarasekara; Indika Wijesinghe; B Parththipan; Senaka Rajapakse
Journal:  Trans R Soc Trop Med Hyg       Date:  2014-09-28       Impact factor: 2.184

6.  Leptospirosis.

Authors:  L H Turner
Journal:  Br Med J       Date:  1969-01-25
  6 in total
  1 in total

1.  Enzyme immunoassays (EIA) for serodiagnosis of human leptospirosis: specific IgG3/IgG1 isotyping may further inform diagnosis of acute disease.

Authors:  Elsa Fortes-Gabriel; Mariana Soares Guedes; Advait Shetty; Charles Klazer Gomes; Teresa Carreira; Maria Luísa Vieira; Lisa Esteves; Luísa Mota-Vieira; Maria Gomes-Solecki
Journal:  PLoS Negl Trop Dis       Date:  2022-02-23
  1 in total

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