Literature DB >> 29016308

Absence of Loa loa Microfilaremia among Newly Arrived Congolese Refugees in Texas.

Jessica Montour1, Deborah Lee2, Cathy Snider1, Emily S Jentes2, William Stauffer3,2.   

Abstract

The Centers for Disease Control and Prevention recommends that refugees at risk of Loa loa infection be tested for microfilaria before treatment with ivermectin. We report observational results of this approach in African refugees in Texas. Daytime blood smears were performed for microfilaria on at-risk African refugees who arrived in Texas from July 1, 2014 through December 30, 2016. Clinics were asked if there were any adverse events reported among those who received ivermectin. Of the 422 persons screened, 346 (82%) were born in L. loa-endemic countries, with 332 (96%) of these being born in the Democratic Republic of Congo. No smears detected microfilaria, and all received presumptive ivermectin with no reports of significant adverse events. In this investigation, the prevalence of significant microfilarial load in sub-Saharan African refugees appeared to be low, and ivermectin treatment was safe and well tolerated.

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Year:  2017        PMID: 29016308      PMCID: PMC5805057          DOI: 10.4269/ajtmh.17-0337

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  8 in total

1.  High-cost generic drugs--implications for patients and policymakers.

Authors:  Jonathan D Alpern; William M Stauffer; Aaron S Kesselheim
Journal:  N Engl J Med       Date:  2014-11-13       Impact factor: 91.245

2.  Serious reactions after mass treatment of onchocerciasis with ivermectin in an area endemic for Loa loa infection.

Authors:  J Gardon; N Gardon-Wendel; J Kamgno; J P Chippaux; M Boussinesq
Journal:  Lancet       Date:  1997-07-05       Impact factor: 79.321

3.  Point-of-care quantification of blood-borne filarial parasites with a mobile phone microscope.

Authors:  Michael V D'Ambrosio; Matthew Bakalar; Sasisekhar Bennuru; Clay Reber; Arunan Skandarajah; Lina Nilsson; Neil Switz; Joseph Kamgno; Sébastien Pion; Michel Boussinesq; Thomas B Nutman; Daniel A Fletcher
Journal:  Sci Transl Med       Date:  2015-05-06       Impact factor: 17.956

4.  Effect of a single dose (600 mg) of albendazole on Loa loa microfilaraemia.

Authors:  J Kamgno; M Boussinesq
Journal:  Parasite       Date:  2002-03       Impact factor: 3.000

5.  A comparative trial of a single-dose ivermectin versus three days of albendazole for treatment of Strongyloides stercoralis and other soil-transmitted helminth infections in children.

Authors:  H Marti; H J Haji; L Savioli; H M Chwaya; A F Mgeni; J S Ameir; C Hatz
Journal:  Am J Trop Med Hyg       Date:  1996-11       Impact factor: 2.345

Review 6.  Ivermectin, 'wonder drug' from Japan: the human use perspective.

Authors:  Andy Crump; Satoshi Ōmura
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2011       Impact factor: 3.493

7.  The geographic distribution of Loa loa in Africa: results of large-scale implementation of the Rapid Assessment Procedure for Loiasis (RAPLOA).

Authors:  Honorat Gustave Marie Zouré; Samuel Wanji; Mounkaïla Noma; Uche Veronica Amazigo; Peter J Diggle; Afework Hailemariam Tekle; Jan H F Remme
Journal:  PLoS Negl Trop Dis       Date:  2011-06-28

8.  Neglected tropical diseases in sub-saharan Africa: review of their prevalence, distribution, and disease burden.

Authors:  Peter J Hotez; Aruna Kamath
Journal:  PLoS Negl Trop Dis       Date:  2009-08-25
  8 in total

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