Literature DB >> 2901611

Effect of Phyllanthus amarus on chronic carriers of hepatitis B virus.

S P Thyagarajan1, S Subramanian, T Thirunalasundari, P S Venkateswaran, B S Blumberg.   

Abstract

In a preliminary study, carriers of hepatitis B virus were treated with a preparation of the plant Phyllanthus amarus for 30 days. 22 of 37 (59%) treated patients had lost hepatitis B surface antigen when tested 15-20 days after the end of the treatment compared with only 1 of 23 (4%) placebo-treated controls. Some subjects have been followed for up to 9 months. In no case has the surface antigen returned. Clinical observation revealed few or no toxic effects. The encouraging results of this preliminary study recommend continued evaluation of this plant and the active principles isolated from it.

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Year:  1988        PMID: 2901611     DOI: 10.1016/s0140-6736(88)92416-6

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  35 in total

Review 1.  Chinese medicinal herbs for chronic hepatitis B.

Authors:  J P Liu; H McIntosh; H Lin
Journal:  Cochrane Database Syst Rev       Date:  2001

2.  Tackling the growing threat of dengue: Phyllanthus niruri-mediated synthesis of silver nanoparticles and their mosquitocidal properties against the dengue vector Aedes aegypti (Diptera: Culicidae).

Authors:  Udaiyan Suresh; Kadarkarai Murugan; Giovanni Benelli; Marcello Nicoletti; Donald R Barnard; Chellasamy Panneerselvam; Palanisamy Mahesh Kumar; Jayapal Subramaniam; Devakumar Dinesh; Balamurugan Chandramohan
Journal:  Parasitol Res       Date:  2015-02-12       Impact factor: 2.289

Review 3.  Hepatology.

Authors:  P M Harrison; J Y Lau; R Williams
Journal:  Postgrad Med J       Date:  1991-08       Impact factor: 2.401

Review 4.  The role of plant-derived drugs and herbal medicines in healthcare.

Authors:  P A De Smet
Journal:  Drugs       Date:  1997-12       Impact factor: 9.546

Review 5.  Herbal medicines for liver diseases.

Authors:  Radha K Dhiman; Yogesh K Chawla
Journal:  Dig Dis Sci       Date:  2005-10       Impact factor: 3.199

Review 6.  Chinese medicinal herbs for asymptomatic carriers of hepatitis B virus infection.

Authors:  J P Liu; H McIntosh; H Lin
Journal:  Cochrane Database Syst Rev       Date:  2001

7.  Efficacy of early treatment on 52 patients with preneoplastic hepatitis B virus-associated hepatocellular carcinoma by compound Phyllanthus Urinaria L.

Authors:  Guang-dong Tong; Xi Zhang; Da-qiao Zhou; Chun-shan Wei; Jin-song He; Chun-ling Xiao; Xin-liang Liu; Ying-jun Zheng; Si-nuan Chen; Hai-hong Tang
Journal:  Chin J Integr Med       Date:  2013-03-25       Impact factor: 1.978

8.  Antioxidant potential of aqueous extract of Phyllanthus amarus in rats.

Authors:  R Karuna; S Sreenivasa Reddy; R Baskar; D Saralakumari
Journal:  Indian J Pharmacol       Date:  2009-04       Impact factor: 1.200

9.  Larvicidal activity of some Euphorbiaceae plant extracts against Aedes aegypti and Culex quinquefasciatus (Diptera: Culicidae).

Authors:  A Abdul Rahuman; Geetha Gopalakrishnan; P Venkatesan; Kannappan Geetha
Journal:  Parasitol Res       Date:  2007-12-29       Impact factor: 2.289

10.  Organic nitrogen stimulates caulogenesis from hypocotyl callus of Phyllanthus fraternus.

Authors:  S Rajasubramaniam; P Pardha Saradhi
Journal:  Plant Cell Rep       Date:  1994-08       Impact factor: 4.570

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