| Literature DB >> 2901517 |
G Steventon1, A C Williams, R H Waring, H S Pall, D Adams.
Abstract
Debrisoquine, carbocysteine, and paracetamol were selected as safe drugs to investigate the ability of the liver's microsomal system to oxidise carbon, oxidise sulphur, and conjugate sulphate in patients with motor neuron disease (MND), other hospital patients, and healthy volunteers. Subjects with poor sulphur-oxidising and sulphur-conjugating activities were heavily over-represented in the MND group.Entities:
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Year: 1988 PMID: 2901517 DOI: 10.1016/s0140-6736(88)90467-9
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321