| Literature DB >> 2901515 |
T C Harvey1, M E Raichle, M H Winterborn, J Jensen, N A Lassen, N V Richardson, A R Bradwell.
Abstract
The effect of adding CO2 to inhaled air in six subjects with acute mountain sickness was investigated during a medical expedition to 5400 m.3% CO2 in ambient air increased ventilation and resulted in a rise in PaO2 of between 24% and 40%. There was a 9-28% increase in PaCO2 and a reduction of the respiratory alkalosis normally seen at high altitude. Symptoms of acute mountain sickness were rapidly relieved. In three subjects cerebral blood flow increased by 17-39%, so that oxygen delivery to the brain would have been considerably improved. This study confirms earlier suggestions of the beneficial effect of CO2 inhalation at high altitude.Entities:
Mesh：
Substances：
Year: 1988 PMID： 2901515 DOI： 10.1016/s0140-6736(88)90465-5
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321