Literature DB >> 2900923

Effect of fenamates on prostaglandin E receptor binding.

M C Rees1, R Cañete-Solér, A López Bernal, A C Turnbull.   

Abstract

The effect of fenamates on prostaglandin E receptor binding was examined in myometrial samples collected at hysterectomy. Sodium meclofenamate and mefenamic acid inhibited binding of PGE2 to its specific receptor in a dose-dependent manner, with an ED50 of 20 mumol/l and 200 mumol/l, respectively.

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Year:  1988        PMID： 2900923     DOI： 10.1016/s0140-6736(88)92660-8

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


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