Literature DB >> 2900808

Fine mapping of gene probes and anonymous DNA fragments to the long arm of chromosome 16.

D F Callen1, V J Hyland, E G Baker, A Fratini, R N Simmers, J C Mulley, G R Sutherland.   

Abstract

The fragile site, FRA16B, at 16q22.100 and four different translocations with breakpoints at 16q22.102, 16q22.105, 16q22.108, and 16q22.3 were used to locate and order DNA probes. This was achieved by Southern analysis of a somatic cell hybrid panel containing portions of chromosome 16 and by in situ hybridization. The anonymous DNA fragments D16S6, D16S10, and D16S11 were proximal to FRA16B and located at 16q13----q22.100. D16S4 and LCAT were located at 16q22.100----q22.102. TAT and HP were located at 16q22.105----q22.108. CTRB was located distal to 16q22.105 and therefore is in the distal half of 16q22. The order of markers in this region was determined as centromere-D16S6, D16S11, D16S10, MT-FRA16B-D16S4, LCAT-HP,TAT,CTRB-APRT- telomere. Linkage studies to determine map distances between the closest markers flanking the fragile site are now in progress.

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Year:  1988        PMID: 2900808     DOI: 10.1016/0888-7543(88)90096-1

Source DB:  PubMed          Journal:  Genomics        ISSN: 0888-7543            Impact factor:   5.736


  14 in total

1.  Regional assignment of the human uroporphyrinogen III synthase (UROS) gene to chromosome 10q25.2----q26.3.

Authors:  K H Astrin; C A Warner; H W Yoo; P J Goodfellow; S F Tsai; R J Desnick
Journal:  Hum Genet       Date:  1991-05       Impact factor: 4.132

2.  The interleukin-7 receptor gene is at 5p13.

Authors:  M Lynch; E Baker; L S Park; G R Sutherland; R G Goodwin
Journal:  Hum Genet       Date:  1992-07       Impact factor: 4.132

3.  Molecular analysis of human chromosome 16 cosmid clones containing NotI sites.

Authors:  T Lerner; G Wright; B Leverone; W Dackowski; D Shook; M A Anderson; K Klinger; D Callen; G Landes
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 4.  Mouse chromosome 8.

Authors:  J D Ceci
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

5.  The isochromosome 18p syndrome: confirmation of cytogenetic diagnosis in nine cases by in situ hybridization.

Authors:  D F Callen; C J Freemantle; M L Ringenbergs; E Baker; H J Eyre; D Romain; E A Haan
Journal:  Am J Hum Genet       Date:  1990-09       Impact factor: 11.025

6.  Assignment of anonymous DNA probes to specific intervals of human chromosomes 16 and X.

Authors:  V J Hyland; K E Fernandez; D F Callen; R N MacKinnon; E Baker; K Friend; G R Sutherland
Journal:  Hum Genet       Date:  1989-08       Impact factor: 4.132

7.  An MspI RFLP at D16S10.

Authors:  A K Gedeon; J C Mulley; A Fratini
Journal:  Nucleic Acids Res       Date:  1989-03-11       Impact factor: 16.971

8.  A linkage group with FRA16B (the fragile site at 16q22.1).

Authors:  J C Mulley; V J Hyland; A Fratini; L J Bates; A K Gedeon; G R Sutherland
Journal:  Hum Genet       Date:  1989-05       Impact factor: 4.132

9.  Chromosomal localization of ARSB, the gene for human N-acetylgalactosamine-4-sulphatase.

Authors:  T Litjens; E G Baker; K R Beckmann; C P Morris; J J Hopwood; D F Callen
Journal:  Hum Genet       Date:  1989-04       Impact factor: 4.132

10.  Phylogenetic conservation and physical mapping of members of the H6 homeobox gene family.

Authors:  H S Stadler; J C Murray; N J Leysens; P J Goodfellow; M Solursh
Journal:  Mamm Genome       Date:  1995-06       Impact factor: 2.957

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