Literature DB >> 2900060

Ethanol potentiates GABA- and glycine-induced chloride currents in chick spinal cord neurons.

J J Celentano1, T T Gibbs, D H Farb.   

Abstract

The effects of acute ethanol exposure of chick spinal cord neurons were studied in tissue culture, using whole-cell voltage-clamp techniques. Results indicate that ethanol produces a persistent increase in the sensitivity of spinal neurons to GABA and glycine, with no change in input resistance or resting membrane potential. Glutamate responses, in contrast, are unaffected by ethanol.

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Year:  1988        PMID: 2900060     DOI: 10.1016/0006-8993(88)90098-4

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  37 in total

1.  Differential effects of ethanol on glycine uptake mediated by the recombinant GLYT1 and GLYT2 glycine transporters.

Authors:  E Núñez; B López-Corcuera; R Martínez-Maza; C Aragón
Journal:  Br J Pharmacol       Date:  2000-02       Impact factor: 8.739

2.  Mode of action of ICS 205,930, a novel type of potentiator of responses to glycine in rat spinal neurones.

Authors:  D Chesnoy-Marchais
Journal:  Br J Pharmacol       Date:  1999-02       Impact factor: 8.739

3.  Cerebellar GABAA receptor binding and function in vitro in two rat lines developed for high and low alcohol sensitivity.

Authors:  M Uusi-Oukari; E R Korpi
Journal:  Neurochem Res       Date:  1989-08       Impact factor: 3.996

4.  Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit.

Authors:  Yuri A Blednov; Jill M Benavidez; Gregg E Homanics; R Adron Harris
Journal:  J Pharmacol Exp Ther       Date:  2011-10-28       Impact factor: 4.030

5.  Effects of acute ethanol or amphetamine administration on the acoustic startle response and prepulse inhibition in adolescent and adult rats.

Authors:  Steven Craig Brunell; Linda Patia Spear
Journal:  Psychopharmacology (Berl)       Date:  2006-04-25       Impact factor: 4.530

Review 6.  Acute alcohol action and desensitization of ligand-gated ion channels.

Authors:  Alex M Dopico; David M Lovinger
Journal:  Pharmacol Rev       Date:  2009-03-06       Impact factor: 25.468

7.  Evaluation of GABAergic neuroactive steroid 3alpha-hydroxy-5alpha-pregnane-20-one as a neurobiological substrate for the anti-anxiety effect of ethanol in rats.

Authors:  Khemraj Hirani; Ajay N Sharma; Nishant S Jain; Rajesh R Ugale; Chandrabhan T Chopde
Journal:  Psychopharmacology (Berl)       Date:  2005-02-18       Impact factor: 4.530

8.  GABA receptor-channel complex as a target site of mercury, copper, zinc, and lanthanides.

Authors:  T Narahashi; J Y Ma; O Arakawa; E Reuveny; M Nakahiro
Journal:  Cell Mol Neurobiol       Date:  1994-12       Impact factor: 5.046

Review 9.  The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypes.

Authors:  W Hevers; H Lüddens
Journal:  Mol Neurobiol       Date:  1998-08       Impact factor: 5.590

Review 10.  Ethanol effects on glycinergic transmission: From molecular pharmacology to behavior responses.

Authors:  Carlos F Burgos; Braulio Muñoz; Leonardo Guzman; Luis G Aguayo
Journal:  Pharmacol Res       Date:  2015-07-06       Impact factor: 7.658

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