Literature DB >> 2899543

Studies on the human chromosome 3 centromere with a newly cloned alphoid DNA probe.

O Delattre1, A Bernard, B Malfoy, F Marlhens, E Viegas-Pequignot, C Brossard, O Haguenauer, N Creau-Goldberg, V C N'guyen, B Dutrillaux.   

Abstract

Starting from a chromosome-specific DNA library, we have isolated a human chromosome-specific satellite DNA sequence. This sequence of 635 base pairs (bp) consists of 3.7 alpha DNA monomers of 170-171 bp. Under high stringency it hybridizes to the centromere of chromosome 3 in a region composed of 2,750 bp tandem repeats characterized by the regular spacing of Hind III and TaqI restriction enzyme recognition sites. It has diverged and undergone amplification after the human speciation. The amplification allows an easy monitoring of the chromosome 3 centromere by in situ hybridization with a nonradioactive probe.

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Year:  1988        PMID： 2899543     DOI： 10.1159/000153777

Source DB:  PubMed          Journal:  Hum Hered        ISSN： 0001-5652            Impact factor:   0.444


  6 in total

Review 1.  A survey of the genomic distribution of alpha satellite DNA on all the human chromosomes, and derivation of a new consensus sequence.

Authors:  K H Choo; B Vissel; A Nagy; E Earle; P Kalitsis
Journal:  Nucleic Acids Res       Date:  1991-03-25       Impact factor: 16.971

2.  Mapping of single-copy DNA sequences on human chromosomes by in situ hybridization with biotinylated probes: enhancement of detection sensitivity by intensified-fluorescence digital-imaging microscopy.

Authors:  E Viegas-Pequignot; B Dutrillaux; H Magdelenat; M Coppey-Moisan
Journal:  Proc Natl Acad Sci U S A       Date:  1989-01       Impact factor: 11.205

3.  Consensus higher order repeats and frequency of string distributions in human genome.

Authors:  Vladimir Paar; Ivan Basar; Marija Rosandić; Matko Gluncić
Journal:  Curr Genomics       Date:  2007-04       Impact factor: 2.236

4.  Chromosome specificity of satellite DNAs: short- and long-range organization of a diverged dimeric subset of human alpha satellite from chromosome 3.

Authors:  J S Waye; H F Willard
Journal:  Chromosoma       Date:  1989-05       Impact factor: 4.316

5.  A human alpha satellite DNA subset specific for chromosome 12.

Authors:  A Baldini; M Rocchi; N Archidiacono; O J Miller; D A Miller
Journal:  Am J Hum Genet       Date:  1990-04       Impact factor: 11.025

6.  Concerted evolution of alpha satellite DNA: evidence for species specificity and a general lack of sequence conservation among alphoid sequences of higher primates.

Authors:  J S Waye; H F Willard
Journal:  Chromosoma       Date:  1989-10       Impact factor: 4.316
  6 in total

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