Mags Beksinska1, Ross Greener2, Jenni Smit2, Busi Maphumulo2, Nonhlanhla Mphili2, Maggie Kilbourne-Brook3, Patricia S Coffey3. 1. MatCH Research Unit [Maternal, Adolescent and Child Health Research Unit], Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, Durban, 3629, South Africa. mbeksinska@matchresearch.co.za. 2. MatCH Research Unit [Maternal, Adolescent and Child Health Research Unit], Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, Durban, 3629, South Africa. 3. PATH, PO Box 900922, Seattle, WA, 98119, USA.
Abstract
INTRODUCTION: This study aimed to assess acceptability and preferences for the SILCS diaphragm for vaginal gel delivery compared to a prefilled applicator. METHODS: A randomized crossover study among 115 women in South Africa, using both methods during five sex acts. RESULTS: We found no significant differences in acceptability between the two products. Experience of gel leakage after sex was greater when inserted via applicator. More women were interested in SILCS/gel for multipurpose protection (68%) than in either SILCS alone (17%) or microbicide gel alone (14%). CONCLUSIONS: A SILCS gel delivery system for multipurpose prevention seems feasible and acceptable.
RCT Entities:
INTRODUCTION: This study aimed to assess acceptability and preferences for the SILCS diaphragm for vaginal gel delivery compared to a prefilled applicator. METHODS: A randomized crossover study among 115 women in South Africa, using both methods during five sex acts. RESULTS: We found no significant differences in acceptability between the two products. Experience of gel leakage after sex was greater when inserted via applicator. More women were interested in SILCS/gel for multipurpose protection (68%) than in either SILCS alone (17%) or microbicide gel alone (14%). CONCLUSIONS: A SILCS gel delivery system for multipurpose prevention seems feasible and acceptable.
Authors: Emma Smith; Cecilia Milford; Kenneth Ngure; Sara Newmann; Nicholas B Thuo; Susana Berrios; Mags E Beksinska; Nelly Mugo; Larry Rand Journal: Reprod Health Date: 2022-07-30 Impact factor: 3.355
Authors: Danielle M Harris; Anita Dam; Kate Morrison; Chastain Mann; Ashley Jackson; Shannon M Bledsoe; Andrea Rowan; Kim Longfield Journal: Stud Fam Plann Date: 2022-08-03