Ching-Chang Ko1, Dong-Ho Yi2, Dong Joon Lee3, Jane Kwon4, Franklin Garcia-Godoy5, Yong Hoon Kwon6. 1. Department of Orthodontics, School of Dentistry, University of North Carolina, Chapel Hill, NC 27599, USA. 2. Department of Dental Materials, School of Dentistry, Pusan National University, Yangsan 50612, Korea. 3. NC Oral Health Institute, School of Dentistry, University of North Carolina, Chapel Hill, NC 27599, USA. 4. Department of Biological and Environmental Engineering, College of Engineering, Cornell University, Ithaca, NY 14850, USA. 5. University of Tennessee Health Science Center, College of Dentistry, Department of Bioscience Research, Memphis, TN 38163, USA. 6. Department of Dental Materials, School of Dentistry, Pusan National University, Yangsan 50612, Korea. Electronic address: y0k0916@pusan.ac.kr.
Abstract
OBJECTIVE: The aim of this study was to identify the factors derived from the 405nm laser-induced autofluorescence (AF) spectra that could be used to diagnose and stage caries. MATERIALS AND METHODS: Teeth (20 teeth per stage) were classified as sound, stage II, III, and IV based on a visual and tactile inspection. The specimens were re-examined and reclassified based on micro-CT analysis. From the teeth, the AF was obtained using a 405nm laser. Three spectral factors (spectral slope at 550-600nm, area under the curve at 500-590nm, and two-peak ratio between 625 and 667nm) were derived from the AF spectra. Using these factors, the diagnosis and staging of caries were tested, and the results were compared with those of DIAGNOdent. RESULTS: After micro-CT analysis, only 13, 11, and 13 teeth were reclassified as stages II, III, and IV, respectively. The reclassified groups showed less data overlap between the stages, and the spectral slope was 40.1-74.6, 27.5-39.6, 11.1-27.4, and 1.0-9.7 for sound, stage II, III, and IV, respectively. The differentiation of stages III and IV using DIAGNOdent appeared to be difficult due to the considerable data overlap. CONCLUSION: Among the factors tested, the spectral slope at 550-600nm showed the best match with the caries specimens, in which their stage had been identified precisely. CLINICAL SIGNIFICANCE: The 405nm laser-induced AF spectra can be applied to the diagnosis and staging of caries alone or in conjunction with conventional methods, such as visual, tactile, and X-ray inspection.
OBJECTIVE: The aim of this study was to identify the factors derived from the 405nm laser-induced autofluorescence (AF) spectra that could be used to diagnose and stage caries. MATERIALS AND METHODS: Teeth (20 teeth per stage) were classified as sound, stage II, III, and IV based on a visual and tactile inspection. The specimens were re-examined and reclassified based on micro-CT analysis. From the teeth, the AF was obtained using a 405nm laser. Three spectral factors (spectral slope at 550-600nm, area under the curve at 500-590nm, and two-peak ratio between 625 and 667nm) were derived from the AF spectra. Using these factors, the diagnosis and staging of caries were tested, and the results were compared with those of DIAGNOdent. RESULTS: After micro-CT analysis, only 13, 11, and 13 teeth were reclassified as stages II, III, and IV, respectively. The reclassified groups showed less data overlap between the stages, and the spectral slope was 40.1-74.6, 27.5-39.6, 11.1-27.4, and 1.0-9.7 for sound, stage II, III, and IV, respectively. The differentiation of stages III and IV using DIAGNOdent appeared to be difficult due to the considerable data overlap. CONCLUSION: Among the factors tested, the spectral slope at 550-600nm showed the best match with the caries specimens, in which their stage had been identified precisely. CLINICAL SIGNIFICANCE: The 405nm laser-induced AF spectra can be applied to the diagnosis and staging of caries alone or in conjunction with conventional methods, such as visual, tactile, and X-ray inspection.
Authors: Adriana Ribeiro; Christel Rousseau; John Girkin; Andrew Hall; Ronald Strang; C John Whitters; Stephen Creanor; Anderson S L Gomes Journal: J Dent Date: 2005-01 Impact factor: 4.379
Authors: Catherine M C Volgenant; Monique H van der Veen; Johannes J de Soet; Jacob M ten Cate Journal: Eur J Oral Sci Date: 2013-04-19 Impact factor: 2.612