Literature DB >> 28992126

Association Between Vancomycin Trough Concentrations and Duration of Methicillin-Resistant Staphylococcus aureus Bacteremia in Children.

Alice J Hsu1, Rana F Hamdy2, Yanjie Huang3, Jared A Olson4, Shahira Ghobrial5, Jeffrey S Gerber6,7, Adam L Hersh8, Pranita D Tamma9.   

Abstract

In a multicenter retrospective study, we sought to determine the optimal vancomycin trough concentration that would impact the duration of methicillin-resistant Staphylococcus aureus bacteremia in children. We found that a median vancomycin trough concentration of <10 µg/mL within the first 72 hours may be associated with a longer duration of bacteremia compared to a median trough concentration of ≥10 µg/mL.

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Year:  2018        PMID: 28992126     DOI: 10.1093/jpids/pix068

Source DB:  PubMed          Journal:  J Pediatric Infect Dis Soc        ISSN: 2048-7193            Impact factor:   3.164


  7 in total

Review 1.  Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections in Children: a Reappraisal of Vancomycin.

Authors:  Roopali Sharma; Margaret R Hammerschlag
Journal:  Curr Infect Dis Rep       Date:  2019-09-05       Impact factor: 3.725

2.  Implementation of a Vancomycin Dose-Optimization Protocol in Neonates: Impact on Vancomycin Exposure, Biological Parameters, and Clinical Outcomes.

Authors:  Laura Gomez; Diane Boegler; Chloé Epiard; Layli Alin; Julie Arata-Bardet; Yvan Caspar; Thierry Debillon; Françoise Stanke-Labesque; Elodie Gautier-Veyret
Journal:  Antimicrob Agents Chemother       Date:  2022-04-25       Impact factor: 5.938

3.  Impact of initial vancomycin pharmacokinetic/pharmacodynamic parameters on the clinical and microbiological outcomes of methicillin-resistant Staphylococcus aureus bacteremia in children.

Authors:  Reenar Yoo; Hyejin So; Euri Seo; Mina Kim; Jina Lee
Journal:  PLoS One       Date:  2021-04-01       Impact factor: 3.240

4.  Relationship between Vancomycin Trough Serum Concentrations and Clinical Outcomes in Children: a Systematic Review and Meta-Analysis.

Authors:  Lu Cao; Zhuo Li; Peng Zhang; Suyun Yong
Journal:  Antimicrob Agents Chemother       Date:  2022-07-13       Impact factor: 5.938

5.  Population Pharmacokinetics and Dose Optimization of Vancomycin in Critically Ill Children.

Authors:  Kannan Sridharan; Mohammad Yaseen Abbasi; Mwila Mulubwa
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2021-06-22       Impact factor: 2.441

6.  Assessment of Vancomycin Pharmacokinetics and Dose Regimen Optimisation in Preterm Neonates.

Authors:  Mwila Mulubwa; Heletje Aletta Griesel; Pierre Mugabo; Ricky Dippenaar; Lizelle van Wyk
Journal:  Drugs R D       Date:  2020-06

7.  Vancomycin is commonly under-dosed in critically ill children and neonates.

Authors:  Natasha Sosnin; Nigel Curtis; Noel Cranswick; Roberto Chiletti; Amanda Gwee
Journal:  Br J Clin Pharmacol       Date:  2019-08-30       Impact factor: 4.335

  7 in total

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