| Literature DB >> 2899154 |
J G Prieto1, J P Barrio, A I Alvarez, G Gómez.
Abstract
The absorptive behaviour of ofloxacin, a quinolone antibacterial agent, was studied following recirculation in small intestine of both male and female rats, at initial doses ranging from 0.125 to 5 mg mL-1. A saturable Michaelis-Menten process is suggested to explain the intestinal absorption. No significant differences were found in the absorption parameters per metabolic weight unit.Entities:
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Year: 1988 PMID： 2899154 DOI： 10.1111/j.2042-7158.1988.tb05223.x
Source DB: PubMed Journal: J Pharm Pharmacol ISSN： 0022-3573 Impact factor: 3.765