| Literature DB >> 28991281 |
Gregorio Campos-Cabrera1, Virginia Campos-Cabrera2, Salvador Campos-Cabrera1, José-Luis Campos-Villagómez1, Alejandra Romero-González3.
Abstract
Myeloproliferative neoplasms are chronic disorders of clonal hematopoietic stem cells, characterized by an overproduction of functional granulocytes, red blood cells and / or platelets, and one of the major complications is the occurrence of venous and arterial thrombotic problems caused by increased platelet aggregation and thrombin generation. In this study 11 cases of primary myelofibrosis (PM) were evaluated and 2 debuted with splanchnic venous thrombosis (SVT); so after seeing the results of this study and of world literature, it is suggested that in patients with SVT, diagnostic methods for PM like the JAK2V617F mutation should be included. Copyright:Entities:
Keywords: JAK2V617F mutation; Mielofibrosis primaria; Mutación JAK2V617F; Myeloproliferative neoplasms; Neoplasias mieloproliferativas; Primary myelofibrosis; Splanchnic vein thrombosis; Trombosis venosa esplácnica
Mesh：
Substances：
Year: 2017 PMID： 28991281 DOI： 10.24875/GMM.17002822
Source DB: PubMed Journal: Gac Med Mex ISSN： 0016-3813 Impact factor: 0.302