Peige Song1,2, Manli Wang1, Xinlei Chang1, Jiawen Wang3, Wei Wei3, Lin An1. 1. Department of Maternal and Child Health, School of Public Health, Peking University, Beijing, China. 2. Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK. 3. Institute of Medical Humanities, Peking University, Beijing, China.
Abstract
AIM: To assess the prevalence of impaired renal function and its associated factors in Chinese children. METHODS: Children aged 7-18 years in China Health and Nutrition Survey (CHNS) 2009 were included as participants, and their anthropometric measurements, blood pressure (BP) and biochemical parameters were taken for analysis. The estimated glomerular filtration rate (eGFR) was calculated by using the Schwartz 'original' formula. RESULTS: The prevalence of estimated glomerular filtration rate (eGFR) < 90 mL/min per 1.73 m2 and <75 mL/min per 1.73 m2 was 10.09% (95% CI: 8.03-12.11) and 1.01% (95% CI: 0.38-1.77), respectively. The prevalence of impaired renal function (eGFR <60 mL/min per 1.73 m2 ) was 0.25%. Age was detected as a negative associated factor whereas hyperuricemia and elevated total cholesterol (TC) were positively associated factors for subjects with eGFR <90 mL/min per 1.73 m2 . In the group of eGFR <75 mL/min per 1.73 m2 , only elevated TC was related to the increased odds of decreased eGFR. CONCLUSION: Our findings underscore the need for large-scale programs to detect and treat the early-stage impaired renal function in the paediatric population in China.
AIM: To assess the prevalence of impaired renal function and its associated factors in Chinese children. METHODS:Children aged 7-18 years in China Health and Nutrition Survey (CHNS) 2009 were included as participants, and their anthropometric measurements, blood pressure (BP) and biochemical parameters were taken for analysis. The estimated glomerular filtration rate (eGFR) was calculated by using the Schwartz 'original' formula. RESULTS: The prevalence of estimated glomerular filtration rate (eGFR) < 90 mL/min per 1.73 m2 and <75 mL/min per 1.73 m2 was 10.09% (95% CI: 8.03-12.11) and 1.01% (95% CI: 0.38-1.77), respectively. The prevalence of impaired renal function (eGFR <60 mL/min per 1.73 m2 ) was 0.25%. Age was detected as a negative associated factor whereas hyperuricemia and elevated total cholesterol (TC) were positively associated factors for subjects with eGFR <90 mL/min per 1.73 m2 . In the group of eGFR <75 mL/min per 1.73 m2 , only elevated TC was related to the increased odds of decreased eGFR. CONCLUSION: Our findings underscore the need for large-scale programs to detect and treat the early-stage impaired renal function in the paediatric population in China.
Authors: S Moe; T Drüeke; J Cunningham; W Goodman; K Martin; K Olgaard; S Ott; S Sprague; N Lameire; G Eknoyan Journal: Kidney Int Date: 2006-06 Impact factor: 10.612
Authors: Andrew S Levey; Josef Coresh; Ethan Balk; Annamaria T Kausz; Adeera Levin; Michael W Steffes; Ronald J Hogg; Ronald D Perrone; Joseph Lau; Garabed Eknoyan Journal: Ann Intern Med Date: 2003-07-15 Impact factor: 25.391