Literature DB >> 28989447

The Where is Norovirus Control Lost (WINCL) Study: an enhanced surveillance project to identify norovirus index cases in care settings in the UK and Ireland.

Evonne T Curran1, Jennie Wilson2, Caroline E Haig3, Colin McCowan3, Alistair Leanord4, Heather Loveday2.   

Abstract

BACKGROUND: Norovirus outbreaks have a significant impact on all care settings; little is known about the index cases from whom these outbreaks initiate. AIM: To identify and categorise norovirus outbreak index cases in care settings.
METHODS: A mixed-methods, multi-centre, prospective, enhanced surveillance study identified and categorised index cases in acute and non-acute care settings.
RESULTS: From 54 participating centres, 537 outbreaks were reported (November 2013 to April 2014): 383 (71.3%) in acute care facilities (ACF); 115 (21.4%) in residential or care homes (RCH) and 39 (7.3%) in other care settings (OCS). Index cases were identified in 424 (79%) outbreaks. Of the 245 index cases who were asymptomatic on admission and not transferred within/into the care setting, 123 (50%) had been an inpatient/resident for 4 days. Four themes emerged: missing the diagnosis, care service under pressure, delay in outbreak control measures and patient/resident location and proximity.
CONCLUSION: The true index case is commonly not identified as the cause of a norovirus outbreak with at least 50% of index cases being misclassified. Unrecognised norovirus cross-transmission occurs frequently suggesting that either Standard Infection Control Precautions (SICPs) are being insufficiently well applied, and or SICPs are themselves are insufficient to prevent outbreaks.

Entities:  

Keywords:  Norovirus; care setting; index case; outbreaks

Year:  2015        PMID: 28989447      PMCID: PMC5074184          DOI: 10.1177/1757177415613133

Source DB:  PubMed          Journal:  J Infect Prev        ISSN: 1757-1782


  24 in total

Review 1.  Environmental transmission of norovirus gastroenteritis.

Authors:  Ben Lopman; Paul Gastañaduy; Geun Woo Park; Aron J Hall; Umesh D Parashar; Jan Vinjé
Journal:  Curr Opin Virol       Date:  2011-12-11       Impact factor: 7.090

2.  Investigation and control of a nosocomial norovirus outbreak in a long-term care facility.

Authors:  Marc Carpentier; Jordan Ollivro; Raoul Baron; Mickaël Le Galudec; Chantal Fauchier; Adissa Minoui-Tran; Christopher Payan; Benoist Lejeune; Ronan Garlantézec
Journal:  Infect Control Hosp Epidemiol       Date:  2011-10       Impact factor: 3.254

Review 3.  The epidemiologic and clinical importance of norovirus infection.

Authors:  Robert L Atmar; Mary K Estes
Journal:  Gastroenterol Clin North Am       Date:  2006-06       Impact factor: 3.806

4.  Norovirus in residential care facilities: does prompt notification of outbreaks help?

Authors:  Craig A Davis; Hassan Vally; Frank H Beard
Journal:  Commun Dis Intell Q Rep       Date:  2011-06

Review 5.  Norovirus introduction routes into nursing homes and risk factors for spread: a systematic review and meta-analysis of observational studies.

Authors:  M Petrignani; J van Beek; G Borsboom; J H Richardus; M Koopmans
Journal:  J Hosp Infect       Date:  2014-12-29       Impact factor: 3.926

6.  Hospitalizations and mortality associated with norovirus outbreaks in nursing homes, 2009-2010.

Authors:  Tarak K Trivedi; Traci DeSalvo; Lore Lee; Aimee Palumbo; Maria Moll; Aaron Curns; Aron J Hall; Manish Patel; Umesh D Parashar; Benjamin A Lopman
Journal:  JAMA       Date:  2012-10-24       Impact factor: 56.272

7.  Institutional risk factors for outbreaks of nosocomial gastroenteritis: survival analysis of a cohort of hospital units in South-west England, 2002-2003.

Authors:  B A Lopman; N Andrews; J Sarangi; I B Vipond; D W G Brown; M H Reacher
Journal:  J Hosp Infect       Date:  2005-06       Impact factor: 3.926

8.  Nosocomial transmission of norovirus is mainly caused by symptomatic cases.

Authors:  Faizel H A Sukhrie; Peter Teunis; Harry Vennema; Cedrick Copra; Matthias F C Thijs Beersma; Jolanda Bogerman; Marion Koopmans
Journal:  Clin Infect Dis       Date:  2012-01-30       Impact factor: 9.079

9.  Gastroenteritis outbreak with norovirus in a Swiss university hospital with a newly identified virus strain.

Authors:  N Khanna; D Goldenberger; P Graber; M Battegay; A F Widmer
Journal:  J Hosp Infect       Date:  2003-10       Impact factor: 3.926

Review 10.  Norovirus in healthcare settings.

Authors:  Miren Iturriza-Gómara; Benjamin Lopman
Journal:  Curr Opin Infect Dis       Date:  2014-10       Impact factor: 4.915

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.