Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Characterization of atrial-natriuretic-factor-receptor-coupled membrane guanylate cyclase from rat and mouse testes.

Literature DB >> 2898940

Characterization of atrial-natriuretic-factor-receptor-coupled membrane guanylate cyclase from rat and mouse testes.

Abstract

Studies with isolated adrenal cells and mouse testicular cells have supported a mediatory role of cyclic GMP in ANF (atrial natriuretic factor)-dependent steroidogenic signal transduction. This concept has been strengthened by the purification and biochemical characterization of a 180 kDa protein, which appears to contain both ANF receptor and guanylate cyclase activities, from rat adrenocortical carcinoma cells. Utilizing the antibody to 180 kDa membrane guanylate cyclase as a probe, we now demonstrate the direct presence of ANF-dependent membrane guanylate cyclase in mouse and rat testes. The antibody blocks the ANF-dependent guanylate cyclase activity in isolated membranes, and Western-blot analysis of the partially purified enzyme reveals a single 180 kDa protein. The presence of this enzyme in mouse and rat testes, together with its previous demonstration in rat adrenocortical carcinoma, represent an important potential biochemical role for this enzyme in receptor-mediated steroidogenic signal transduction.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1988 PMID： 2898940 PMCID： PMC1148997 DOI： 10.1042/bj2510301

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

27 in total

1. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Authors: H Towbin; T Staehelin; J Gordon
Journal: Proc Natl Acad Sci U S A Date: 1979-09 Impact factor: 11.205

2. Adrenocorticotropin-dependent particulate guanylate cyclase in rat adrenal and adrenocortical carcinoma: comparison of its properties with soluble guanylate cyclase and its relationship with ACTH-induced steroidogenesis.

Authors: P Nambi; N V Aiyar; R K Sharma
Journal: Arch Biochem Biophys Date: 1982-09 Impact factor: 4.013

3. Demonstration of ACTH-sensitive particulate guanylate cyclase in adrenocortical carcinoma.

Authors: P Nambi; R K Sharma
Journal: Biochem Biophys Res Commun Date: 1981-05-29 Impact factor: 3.575

4. Purification and characterization of two types of atrial natriuretic factor receptors from bovine adrenal cortex: guanylate cyclase-linked and cyclase-free receptors.

Authors: R Takayanagi; R M Snajdar; T Imada; M Tamura; K N Pandey; K S Misono; T Inagami
Journal: Biochem Biophys Res Commun Date: 1987-04-14 Impact factor: 3.575

5. Solubilization of epinephrine-specific alpha-adrenergic receptors from adrenocortical carcinoma.

Authors: P Nambi; N V Aiyar; R K Sharma
Journal: FEBS Lett Date: 1982-04-05 Impact factor: 4.124

6. Adrenocortical cyclic GMP-dependent protein kinase: purification, characterization, and modification of its activity by calmodulin, and its relationship with steroidogenesis.

Authors: H Ahrens; A K Paul; Y Kuroda; R K Sharma
Journal: Arch Biochem Biophys Date: 1982-05 Impact factor: 4.013

7. Inhibition of aldosterone production by an atrial extract.

Authors: K Atarashi; P J Mulrow; R Franco-Saenz; R Snajdar; J Rapp
Journal: Science Date: 1984-06-01 Impact factor: 47.728

8. Atrial natriuretic factor inhibits the stimulation of aldosterone secretion by angiotensin II, ACTH and potassium in vitro and angiotensin II-induced steroidogenesis in vivo.

Authors: L Chartier; E Schiffrin; G Thibault; R Garcia
Journal: Endocrinology Date: 1984-11 Impact factor: 4.736

9. Specific receptor-mediated inhibition by synthetic atrial natriuretic factor of hormone-stimulated steroidogenesis in cultured bovine adrenal cells.

Authors: A De Léan; K Racz; J Gutkowska; T T Nguyen; M Cantin; J Genest
Journal: Endocrinology Date: 1984-10 Impact factor: 4.736

10. Metabolic regulation of steroidogenesis in isolated adrenal cells of rat. Relationship of adrenocorticotropin-, adenosine 3':5'-monophosphate-and guanosine 3':5'-monophosphate-stimulated steroidogenesis with the activation of protein kinase.

Authors: R K Sharma; N K Ahmed; G Shanker
Journal: Eur J Biochem Date: 1976-11-15

11 in total

Review 1. Evolution of the membrane guanylate cyclase transduction system.

Authors: Rameshwar K Sharma
Journal: Mol Cell Biochem Date: 2002-01 Impact factor: 3.396

2. A structural motif that defines the ATP-regulatory module of guanylate cyclase in atrial natriuretic factor signalling.

Authors: R M Goraczniak; T Duda; R K Sharma
Journal: Biochem J Date: 1992-03-01 Impact factor: 3.857

3. Ubiquitous and bifunctional 180 kDa atrial natriuretic factor-dependent guanylate cyclase.

Authors: R B Marala; R K Sharma
Journal: Mol Cell Biochem Date: 1991-01-16 Impact factor: 3.396

Review 4. Membrane guanylate cyclase is a beautiful signal transduction machine: overview.

Authors: Rameshwar K Sharma
Journal: Mol Cell Biochem Date: 2009-12-03 Impact factor: 3.396

Review 5. Atrial natriuretic peptide in peripheral organs other than the heart.

Authors: A M Vollmar
Journal: Klin Wochenschr Date: 1990-07-17

6. Pre- and post-natal ontogeny of neutral endopeptidase 24-11 ('enkephalinase') studied by in vitro autoradiography in the rat.

Authors: I Dutriez; N Salès; M C Fournié-Zaluski; B P Roques
Journal: Experientia Date: 1992-03-15

7. Interaction of atrial natriuretic factor and endothelin-1 signals through receptor guanylate cyclase in pulmonary artery endothelial cells.

Authors: R B Marala; T Duda; R K Sharma
Journal: Mol Cell Biochem Date: 1993-03-10 Impact factor: 3.396