Literature DB >> 28988814

The Role of the Sinonasal Epithelium in Allergic Rhinitis.

Nyall R London1, Murugappan Ramanathan2.   

Abstract

The sinonasal epithelial barrier is comprised of tight and adherens junction proteins. Disruption of epithelial barrier function has been hypothesized to contribute to allergic disease such as allergic rhinitis through increased passage of antigens and exposure of underlying tissue to these stimuli. Several mechanisms of sinonasal epithelial barrier disruption include antigen proteolytic activity, inflammatory cytokine-mediated tight junction breakdown, or exacerbation from environmental stimuli. Mechanisms of sinonasal epithelial barrier stabilization include corticosteroids and nuclear erythroid 2-related factor 2 (Nrf2) cytoprotective pathway activation. Additional studies will aid in determining the contribution of epithelial barrier function in allergic rhinitis pathophysiology and treatment.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Allergic rhinitis; Epithelial permeability; House dust mite; Sinonasal barrier dysfunction; Tight junctions

Mesh：

Substances：

Year:  2017        PMID： 28988814      PMCID： PMC5752131          DOI： 10.1016/j.otc.2017.08.002

Source DB:  PubMed          Journal:  Otolaryngol Clin North Am        ISSN： 0030-6665            Impact factor:   3.346


  37 in total

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Authors:  P W Hellings; W J Fokkens; C Bachert; C A Akdis; T Bieber; I Agache; M Bernal-Sprekelsen; G W Canonica; P Gevaert; G Joos; V Lund; A Muraro; M Onerci; T Zuberbier; B Pugin; S F Seys; J Bousquet
Journal:  Allergy       Date:  2017-05-21       Impact factor: 13.146

2.  Reversal of cigarette smoke extract-induced sinonasal epithelial cell barrier dysfunction through Nrf2 Activation.

Authors:  Anuj Tharakan; Ashleigh A Halderman; Andrew P Lane; Shyam Biswal; Murugappan Ramanathan
Journal:  Int Forum Allergy Rhinol       Date:  2016-08-31       Impact factor: 3.858

Review 3.  Epidemiology of allergic rhinitis.

Authors:  James W Mims
Journal:  Int Forum Allergy Rhinol       Date:  2014-09       Impact factor: 3.858

4.  Diesel exhaust particles exacerbate allergic rhinitis in mice by disrupting the nasal epithelial barrier.

Authors:  A Fukuoka; K Matsushita; T Morikawa; H Takano; T Yoshimoto
Journal:  Clin Exp Allergy       Date:  2016-01       Impact factor: 5.018

Review 5.  Sublingual immunotherapy for the treatment of allergic rhinoconjunctivitis and asthma: a systematic review.

Authors:  Sandra Y Lin; Nkiruka Erekosima; Julia M Kim; Murugappan Ramanathan; Catalina Suarez-Cuervo; Yohalakshmi Chelladurai; Darcy Ward; Jodi B Segal
Journal:  JAMA       Date:  2013-03-27       Impact factor: 56.272

6.  Association of serum interleukin-33 level and the interleukin-33 genetic variant with Japanese cedar pollinosis.

Authors:  M Sakashita; T Yoshimoto; T Hirota; M Harada; K Okubo; Y Osawa; S Fujieda; Y Nakamura; K Yasuda; K Nakanishi; M Tamari
Journal:  Clin Exp Allergy       Date:  2008-12       Impact factor: 5.018

7.  Impaired barrier function in patients with house dust mite-induced allergic rhinitis is accompanied by decreased occludin and zonula occludens-1 expression.

Authors:  Brecht Steelant; Ricard Farré; Paulina Wawrzyniak; Jochen Belmans; Emily Dekimpe; Hanne Vanheel; Laura Van Gerven; Inge Kortekaas Krohn; Dominique M A Bullens; Jan L Ceuppens; Cezmi A Akdis; Guy Boeckxstaens; Sven F Seys; Peter W Hellings
Journal:  J Allergy Clin Immunol       Date:  2016-02-02       Impact factor: 10.793

8.  Claudin-18 deficiency is associated with airway epithelial barrier dysfunction and asthma.

Authors:  Kelly Sweerus; Marrah Lachowicz-Scroggins; Erin Gordon; Michael LaFemina; Xiaozhu Huang; Mihir Parikh; Cindy Kanegai; John V Fahy; James A Frank
Journal:  J Allergy Clin Immunol       Date:  2016-04-20       Impact factor: 10.793

9.  Physiology and pathophysiology of respiratory mucosa of the nose and the paranasal sinuses.

Authors:  Achim G Beule
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2011-04-27

10.  Broad Th2 neutralization and anti-inflammatory action of pentosan polysulfate sodium in experimental allergic rhinitis.

Authors:  Caroline Sanden; Michiko Mori; Prajakta Jogdand; Jimmie Jönsson; Ravi Krishnan; Xiangdong Wang; Jonas S Erjefält
Journal:  Immun Inflamm Dis       Date:  2017-05-12
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  9 in total

Review 1.  Current Insights on the Impact of Proteomics in Respiratory Allergies.

Authors:  Juan Carlos Vizuet-de-Rueda; Josaphat Miguel Montero-Vargas; Miguel Ángel Galván-Morales; Raúl Porras-Gutiérrez-de-Velasco; Luis M Teran
Journal:  Int J Mol Sci       Date:  2022-05-20       Impact factor: 6.208

Review 2.  Sinuses and Common Rhinologic Conditions.

Authors:  Nyall R London; Murugappan Ramanathan
Journal:  Med Clin North Am       Date:  2018-08-18       Impact factor: 5.456

3.  Effect of Nasal Obstructive Disorders on Sinonasal Symptoms in Children with Different Levels of Bronchial Asthma Control.

Authors:  T I Eliseeva; S V Krasilnikova; N A Geppe; S Yu Babaev; E V Tush; O V Khaletskaya; D Yu Ovsyannikov; I I Balabolkin; S K Ignatov; N I Kubysheva
Journal:  Can Respir J       Date:  2018-05-08       Impact factor: 2.409

4.  Reduced occludin and claudin-7 expression is associated with urban locations and exposure to second-hand smoke in allergic rhinitis patients.

Authors:  Siti Muhamad Nur Husna; Che Othman Siti Sarah; Hern-Tze Tina Tan; Norasnieda Md Shukri; Noor Suryani Mohd Ashari; Kah Keng Wong
Journal:  Sci Rep       Date:  2021-01-13       Impact factor: 4.379

5.  Higher Wheal Sizes of Dermatophagoides farinae Sensitization Exhibit Worse Nasal Symptoms in Allergic Rhinitis Patients.

Authors:  Siti Muhamad Nur Husna; Norasnieda Md Shukri; Hern-Tze Tina Tan; Noor Suryani Mohd Ashari; Kah Keng Wong
Journal:  Front Med (Lausanne)       Date:  2022-02-28

Review 6.  Nasal Epithelial Barrier Integrity and Tight Junctions Disruption in Allergic Rhinitis: Overview and Pathogenic Insights.

Authors:  Siti Muhamad Nur Husna; Hern-Tze Tina Tan; Norasnieda Md Shukri; Noor Suryani Mohd Ashari; Kah Keng Wong
Journal:  Front Immunol       Date:  2021-05-21       Impact factor: 7.561

Review 7.  Airway Epithelial Dynamics in Allergy and Related Chronic Inflammatory Airway Diseases.

Authors:  Anu Laulajainen-Hongisto; Sanna Katriina Toppila-Salmi; Annika Luukkainen; Robert Kern
Journal:  Front Cell Dev Biol       Date:  2020-03-27

8.  Zonula occludens and nasal epithelial barrier integrity in allergic rhinitis.

Authors:  Che Othman Siti Sarah; Norasnieda Md Shukri; Noor Suryani Mohd Ashari; Kah Keng Wong
Journal:  PeerJ       Date:  2020-09-04       Impact factor: 2.984

9.  Yiqi Jiemin decoction alleviates allergic rhinitis in a guinea pig model by suppressing inflammation, restoring Th1/Th2 balance, and improving cellular metabolism.

Authors:  Zhanfeng Yan; Lili Liu; Jingjing Yuan; Lulu Jiao; Mo Zhou; Jinfeng Liu; Xiaohui Wen; Siming Liu; Pengpeng Hao; Jianhua Liu; Wei Wu
Journal:  Aging (Albany NY)       Date:  2021-07-27       Impact factor: 5.682
  9 in total

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