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Literature DB >> 2898778

The effects of drugs on the formation of Theileria annulata merozoites in vitro.

F M Fritsch¹, H Mehlhorn, E Schein, M Hauser.

Abstract

The effects of colchicine, taxol, dinitrophenol, sodium azide, TLA-144, and obioactin on Theileria annulata schizonts were tested in vitro and studied by means of light and electron microscopy. Colchicine (0.001-5 microM) and taxol (1 microM) completely inhibited the mitosis of the host cell. This resulted in higher numbers of schizont nuclei after 96 h, since the division of the parasites was apparently not affected. Increasing numbers of schizont nuclei were also obtained after incubation of parasitized lymphocytes for 7 day at 41 degrees C with a daily medium exchange.

Entities: Chemical Disease Species

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Year: 1988 PMID： 2898778 DOI： 10.1007/bf00539455

Source DB: PubMed Journal: Parasitol Res ISSN： 0932-0113 Impact factor: 2.289

8 in total

1. Immunization to control East Coast Fever.

Authors: T T Dolan
Journal: Parasitol Today Date: 1987-01

2. Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

Authors: A Böyum
Journal: Scand J Clin Lab Invest Suppl Date: 1968

2 in total

1. Stage independent chloroquine resistance and chloroquine toxicity revealed via spinning disk confocal microscopy.

Authors: Bojana Gligorijevic; Kyle Purdy; David A Elliott; Roland A Cooper; Paul D Roepe
Journal: Mol Biochem Parasitol Date: 2008-01-09 Impact factor: 1.759

2. Effects of halofuginone lactate on lymphocytes and MDBK cells infected with Theileria annulata and/or vesicular stomatitis virus (VSV): an in vitro study.

Authors: H Mehlhorn; W Raether
Journal: Parasitol Res Date: 1988 Impact factor: 2.289

2 in total

The effects of drugs on the formation of Theileria annulata merozoites in vitro.

1. Immunization to control East Coast Fever.

2. Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

3. Transition of developmental stages of Theileria parva in vitro at high temperature.

4. Cultivation of three species of Theileria in lymphoid cells in vitro.

5. Simulation in vitro of bovine host cycle of Theileria parva.

Review 6. The piroplasms: life cycle and sexual stages.

7. Letter: Infection and transformation of bovine lymphoid cells in vitro by infective particles of Theileria parva.

8. Immunity in theileriosis.

1. Stage independent chloroquine resistance and chloroquine toxicity revealed via spinning disk confocal microscopy.

2. Effects of halofuginone lactate on lymphocytes and MDBK cells infected with Theileria annulata and/or vesicular stomatitis virus (VSV): an in vitro study.