Literature DB >> 28986209

Effects of prenatal alcohol exposure in a prospective sample of young adults: Mental health, substance use, and difficulties with the legal system.

Mary Ellen Lynch1, Julie A Kable2, Claire D Coles3.   

Abstract

INTRODUCTION: Few studies have focused on the transition to adulthood in adults with prenatal alcohol exposure (PAE). In this study, we examine the occurrence of problem behavior at this transition, including mental health problems, substance use, and difficulties with the legal system. The sample is prospective and provides an opportunity to examine effects of a wide range of prenatal exposure. Adults with PAE were expected to show more problem behavior; the impact of level of exposure was examined as well.
METHOD: The sample was drawn from a predominantly low-income, African-American population. Mothers of the alcohol-exposed participants (n=123) and those in the non-exposed SES-Control group (CONT) (n=59) were recruited at a prenatal visit when information on alcohol and drug use during pregnancy was collected. A disability contrast group (n=54) was recruited at adolescence. The adults with PAE were assigned to three groups varying in physical and cognitive effects of exposure. This report is based on the adults' responses to interviews or questionnaires on problem behavior and laboratory tests related to substance use.
RESULTS: Adults with PAE showed more problem behavior in all three areas than adults from the CONT group. For mental health problems, the exposed group showing cognitive, but not physical effects, had the highest scores; their scores were similar, however, to those of the disability contrast group on several scales. Results for outcomes on substance use and legal difficulties were less consistent, but, when significant effects occurred, the group that was exposed, but neither physically nor cognitively affected, was more likely to show negative outcomes. Males in this group were most involved in these behaviors.
CONCLUSION: Effects of PAE continue into early adulthood and affect mental health problems, substance use, and interactions with the legal system. Adults who are exposed, but less physically affected, seem to be the most involved in problem behavior. More research is necessary to examine environmental effects in conjunction with PAE on these outcomes and to provide a basis for developing potential interventions.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Legal difficulties; Mental health; Prenatal alcohol exposure; Substance use; Transition to adulthood

Mesh:

Substances:

Year:  2017        PMID: 28986209      PMCID: PMC5739524          DOI: 10.1016/j.ntt.2017.10.001

Source DB:  PubMed          Journal:  Neurotoxicol Teratol        ISSN: 0892-0362            Impact factor:   3.763


  38 in total

Review 1.  Prevalence and epidemiologic characteristics of FASD from various research methods with an emphasis on recent in-school studies.

Authors:  Philip A May; J Phillip Gossage; Wendy O Kalberg; Luther K Robinson; David Buckley; Melanie Manning; H Eugene Hoyme
Journal:  Dev Disabil Res Rev       Date:  2009

Review 2.  Defining the behavioral phenotype in children with fetal alcohol spectrum disorders: a review.

Authors:  P W Kodituwakku
Journal:  Neurosci Biobehav Rev       Date:  2006-08-23       Impact factor: 8.989

3.  A Comparison Among 5 Methods for the Clinical Diagnosis of Fetal Alcohol Spectrum Disorders.

Authors:  Claire D Coles; Amanda R Gailey; Jennifer G Mulle; Julie A Kable; Mary Ellen Lynch; Kenneth Lyons Jones
Journal:  Alcohol Clin Exp Res       Date:  2016-03-29       Impact factor: 3.455

4.  Prevalence and characteristics of fetal alcohol spectrum disorders.

Authors:  Philip A May; Amy Baete; Jaymi Russo; Amy J Elliott; Jason Blankenship; Wendy O Kalberg; David Buckley; Marita Brooks; Julie Hasken; Omar Abdul-Rahman; Margaret P Adam; Luther K Robinson; Melanie Manning; H Eugene Hoyme
Journal:  Pediatrics       Date:  2014-11       Impact factor: 7.124

5.  In utero alcohol exposure and prediction of alcohol disorders in early adulthood: a birth cohort study.

Authors:  Rosa Alati; Abdullah Al Mamun; Gail M Williams; Michael O'Callaghan; Jake Moses Najman; William Bor
Journal:  Arch Gen Psychiatry       Date:  2006-09

Review 6.  Fetal alcohol spectrum disorders: an overview for pediatric and adolescent care providers.

Authors:  Yasmin Suzanne N Senturias
Journal:  Curr Probl Pediatr Adolesc Health Care       Date:  2014-04

7.  Examining delinquency in adolescents differentially prenatally exposed to alcohol: the role of proximal and distal risk factors.

Authors:  Mary Ellen Lynch; Claire D Coles; Tammy Corley; Arthur Falek
Journal:  J Stud Alcohol       Date:  2003-09

8.  A 21-year longitudinal analysis of the effects of prenatal alcohol exposure on young adult drinking.

Authors:  John S Baer; Paul D Sampson; Helen M Barr; Paul D Connor; Ann P Streissguth
Journal:  Arch Gen Psychiatry       Date:  2003-04

9.  Fetal alcohol syndrome--Alaska, Arizona, Colorado, and New York, 1995-1997.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2002-05-24       Impact factor: 17.586

10.  Effect of fetal alcohol exposure on adult symptoms of nicotine, alcohol, and drug dependence.

Authors:  W R Yates; R J Cadoret; E P Troughton; M Stewart; T S Giunta
Journal:  Alcohol Clin Exp Res       Date:  1998-06       Impact factor: 3.455

View more
  7 in total

Review 1.  Prenatal risk factors for internalizing and externalizing problems in childhood.

Authors:  Joyce Tien; Gary D Lewis; Jianghong Liu
Journal:  World J Pediatr       Date:  2019-10-15       Impact factor: 2.764

2.  Prenatal alcohol exposure and mental health at midlife: A preliminary report on two longitudinal cohorts.

Authors:  Claire D Coles; Therese M Grant; Julie A Kable; Susan A Stoner; Alexandra Perez
Journal:  Alcohol Clin Exp Res       Date:  2022-02-14       Impact factor: 3.455

3.  Alterations in Insulin Levels in Adults with Prenatal Alcohol Exposure.

Authors:  Julie A Kable; Puja K Mehta; Claire D Coles
Journal:  Alcohol Clin Exp Res       Date:  2021-02-24       Impact factor: 3.455

4.  Evaluation of Brain Alterations and Behavior in Children With Low Levels of Prenatal Alcohol Exposure.

Authors:  Xiangyu Long; Catherine Lebel
Journal:  JAMA Netw Open       Date:  2022-04-01

5.  Aging-Related Behavioral, Adiposity, and Glucose Impairments and Their Association following Prenatal Alcohol Exposure in the C57BL/6J Mouse.

Authors:  Susan M Smith; Eneda Pjetri; Walter B Friday; Brandon H Presswood; Dane K Ricketts; Kathleen R Walter; Sandra M Mooney
Journal:  Nutrients       Date:  2022-03-30       Impact factor: 5.717

6.  Pre-conceptional and Peri-Gestational Maternal Binge Alcohol Drinking Produces Inheritance of Mood Disturbances and Alcohol Vulnerability in the Adolescent Offspring.

Authors:  Anna Brancato; Valentina Castelli; Angela Cavallaro; Gianluca Lavanco; Fulvio Plescia; Carla Cannizzaro
Journal:  Front Psychiatry       Date:  2018-04-23       Impact factor: 4.157

Review 7.  Oral and written communication skills of adolescents with prenatal alcohol exposure (PAE) compared with those with no/low PAE: A systematic review.

Authors:  Natalie R Kippin; Suze Leitão; Rochelle Watkins; Amy Finlay-Jones
Journal:  Int J Lang Commun Disord       Date:  2021-06-16       Impact factor: 2.909

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.