Literature DB >> 28985974

What Is the Role of the Bacterium Propionibacterium acnes in Type 1 Modic Changes? A Review of the Literature.

Mark Georgy1, Mark Stern2, Kieran Murphy3.   

Abstract

This review presents a summary of the pathology and epidemiology of Modic changes and the possible role of Propionibacterium acnes. This information is followed by a synthesis of the most recent clinical research involved in culturing the discs of patients with degenerative disc disease for the presence of bacteria. We also discuss a randomized controlled trial that investigates the effects of antibiotics on patients with chronic low back pain and type 1 Modic changes. We conclude with a brief discussion of the difficulties involved in this research and the significance of the findings.
Copyright © 2017 Canadian Association of Radiologists. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Antibiotics; Disc degenerative disease; Modic changes; P. acnes

Mesh：

Substances：

Year:  2017        PMID： 28985974     DOI： 10.1016/j.carj.2017.07.004

Source DB:  PubMed          Journal:  Can Assoc Radiol J        ISSN： 0846-5371            Impact factor:   2.248


  5 in total

Review 1.  Current concepts for lumbar disc herniation.

Authors:  Thami Benzakour; Vasilios Igoumenou; Andreas F Mavrogenis; Ahmed Benzakour
Journal:  Int Orthop       Date:  2018-11-30       Impact factor: 3.075

Review 2.  Imaging-Based Approach to Extradural Infections of the Spine.

Authors:  Jason F Talbott; Vinil N Shah; Alina Uzelac; Jared Narvid; Rebecca A Dumont; Cynthia T Chin; David M Wilson
Journal:  Semin Ultrasound CT MR       Date:  2018-09-26       Impact factor: 1.875

3.  International Society for the Advancement of Spine Surgery Guideline-Intraosseous Ablation of the Basivertebral Nerve for the Relief of Chronic Low Back Pain.

Authors:  Morgan Lorio; Olivier Clerk-Lamalice; Douglas P Beall; Terrence Julien
Journal:  Int J Spine Surg       Date:  2020-02-29

4.  Modic changes - An evidence-based, narrative review on its patho-physiology, clinical significance and role in chronic low back pain.

Authors:  Vibhu Krishnan Viswanathan; Ajoy Prasad Shetty; S Rajasekaran
Journal:  J Clin Orthop Trauma       Date:  2020-06-18

Review 5.  Evidence for infection in intervertebral disc degeneration: a systematic review.

Authors:  Isabelle Granville Smith; Nathan P Danckert; Maxim B Freidin; Philippa Wells; Julian R Marchesi; Frances M K Williams
Journal:  Eur Spine J       Date:  2021-12-04       Impact factor: 3.134
  5 in total

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