| Literature DB >> 28985557 |
Zhihao Sun1, Jeffrey L Brodsky2.
Abstract
The endoplasmic reticulum-associated degradation (ERAD) pathway facilitates the disposal of terminally misfolded proteins in the early secretory pathway yet spares folding intermediates from being destroyed. Zhang et al. report on a protein complex that acts as a guardian to protect these folding intermediates from being targeted for ERAD.Mesh：
Substances：
Year: 2017 PMID： 28985557 DOI： 10.1016/j.cell.2017.09.023
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582